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Fig. 2 | Environmental Health

Fig. 2

From: Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure

Fig. 2

Wide-scale transcriptome profile alteration in liver and kidneys of Roundup-treated female rats. Liver and kidneys from control rats and animals receiving 0.1 ppb Roundup (50 ng/L glyphosate equivalent dilution) in drinking water were subjected to a full transcriptome microarray analysis. a PCA analysis of transcript cluster expression profiles shows a distinct separation into groups of treated (red) and control (green) rats in both kidney and liver samples. Numbers by data points denote age at time of death in days. b Volcano plots of the liver and kidney transcriptome profiles showing the log 2 fold changes and the –log10 p-values in transcript cluster expression induced by Roundup exposure compared to controls. Data were selected at the cut off values p <0.01 and fold change >1.1. Red dots represent genes commonly disturbed between liver and kidney samples

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