Table 2 Functional clustering of genes derived using the DAVID gene functional classification tool

4.2

GO:0010558 ~ negative regulation of macromolecule biosynthetic process

40

GO:0031327 ~ negative regulation of cellular biosynthetic process

40

GO:0009890 ~ negative regulation of biosynthetic process

40

3.8

GO:0016279 ~ protein-lysine N-methyltransferase activity

7

GO:0016278 ~ lysine N-methyltransferase activity

7

GO:0018024 ~ histone-lysine N-methyltransferase activity

7

GO:0042054 ~ histone methyltransferase activity

7

GO:0008276 ~ protein methyltransferase activity

7

3.3

GO:0000377 ~ RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

15

GO:0000375 ~ RNA splicing, via transesterification reactions

15

GO:0000398 ~ nuclear mRNA splicing, via spliceosome

15

3.3

IPR000504:RNA recognition motif, RNP-1

17

SM00360:RRM

17

IPR012677:Nucleotide-binding, alpha-beta plait

17

2.3

GO:0006099 ~ tricarboxylic acid cycle

6

GO:0046356 ~ acetyl-CoA catabolic process

6

GO:0009109 ~ coenzyme catabolic process

6

GO:0009060 ~ aerobic respiration

6

GO:0051187 ~ cofactor catabolic process

6

rno00020:Citrate cycle (TCA cycle)

6

GO:0006084 ~ acetyl-CoA metabolic process

6

2.2

GO:0030964 ~ NADH dehydrogenase complex

5

GO:0045271 ~ respiratory chain complex I

5

GO:0005747 ~ mitochondrial respiratory chain complex I

5

GO:0005746 ~ mitochondrial respiratory chain

5

2.1

GO:0016571 ~ histone methylation

6

GO:0008213 ~ protein amino acid alkylation

6

GO:0006479 ~ protein amino acid methylation

6

2.1

IPR001440:Tetratricopeptide TPR-1

9

IPR019734:Tetratricopeptide repeat

9

SM00028:TPR

9