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Table 2 Functional clustering of genes derived using the DAVID gene functional classification tool
| ES | Term in DAVID | n | p value | FE | q-value |
|---|---|---|---|---|---|
| 4.2 | GO:0010558 ~ negative regulation of macromolecule biosynthetic process | 40 | 3.7E-05 | 2.0 | 7.9E-3 |
| GO:0031327 ~ negative regulation of cellular biosynthetic process | 40 | 6.0E-05 | 2.0 | 1.1E-2 | |
| GO:0009890 ~ negative regulation of biosynthetic process | 40 | 9.3E-05 | 1.9 | 1.6E-2 | |
| 3.8 | GO:0016279 ~ protein-lysine N-methyltransferase activity | 7 | 5.0E-05 | 9.7 | 5.1E-3 |
| GO:0016278 ~ lysine N-methyltransferase activity | 7 | 5.0E-05 | 9.7 | 5.1E-3 | |
| GO:0018024 ~ histone-lysine N-methyltransferase activity | 7 | 5.0E-05 | 9.7 | 5.1E-3 | |
| GO:0042054 ~ histone methyltransferase activity | 7 | 3.0E-04 | 7.2 | 2.3E-2 | |
| GO:0008276 ~ protein methyltransferase activity | 7 | 2.5E-03 | 5.0 | 7.7E-2 | |
| 3.3 | GO:0000377 ~ RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 15 | 4.8E-04 | 3.0 | 6.0E-2 |
| GO:0000375 ~ RNA splicing, via transesterification reactions | 15 | 4.8E-04 | 3.0 | 6.0E-2 | |
| GO:0000398 ~ nuclear mRNA splicing, via spliceosome | 15 | 4.8E-04 | 3.0 | 6.0E-2 | |
| 3.3 | IPR000504:RNA recognition motif, RNP-1 | 17 | 4.0E-04 | 2.8 | 3.1E-1 |
| SM00360:RRM | 17 | 5.1E-04 | 2.7 | 9.8E-2 | |
| IPR012677:Nucleotide-binding, alpha-beta plait | 17 | 6.1E-04 | 2.7 | 2.5E-1 | |
| 2.3 | GO:0006099 ~ tricarboxylic acid cycle | 6 | 1.7E-03 | 6.6 | 1.5E-1 |
| GO:0046356 ~ acetyl-CoA catabolic process | 6 | 2.1E-03 | 6.3 | 1.7E-1 | |
| GO:0009109 ~ coenzyme catabolic process | 6 | 3.7E-03 | 5.6 | 2.3E-1 | |
| GO:0009060 ~ aerobic respiration | 6 | 4.4E-03 | 5.4 | 2.5E-1 | |
| GO:0051187 ~ cofactor catabolic process | 6 | 8.1E-03 | 4.7 | 3.4E-1 | |
| rno00020:Citrate cycle (TCA cycle) | 6 | 9.2E-03 | 4.5 | 1.7E-1 | |
| GO:0006084 ~ acetyl-CoA metabolic process | 6 | 1.9E-02 | 3.8 | 4.7E-1 | |
| 2.2 | GO:0030964 ~ NADH dehydrogenase complex | 5 | 3.7E-03 | 7.5 | 7.1E-2 |
| GO:0045271 ~ respiratory chain complex I | 5 | 3.7E-03 | 7.5 | 7.1E-2 | |
| GO:0005747 ~ mitochondrial respiratory chain complex I | 5 | 3.7E-03 | 7.5 | 7.1E-2 | |
| GO:0005746 ~ mitochondrial respiratory chain | 5 | 4.3E-02 | 3.7 | 3.1E-1 | |
| 2.1 | GO:0016571 ~ histone methylation | 6 | 1.4E-03 | 6.9 | 1.3E-1 |
| GO:0008213 ~ protein amino acid alkylation | 6 | 1.9E-02 | 3.8 | 4.7E-1 | |
| GO:0006479 ~ protein amino acid methylation | 6 | 1.9E-02 | 3.8 | 4.7E-1 | |
| 2.1 | IPR001440:Tetratricopeptide TPR-1 | 9 | 4.5E-03 | 3.4 | 5.8E-1 |
| IPR019734:Tetratricopeptide repeat | 9 | 1.0E-02 | 2.9 | 7.2E-1 | |
| SM00028:TPR | 9 | 1.2E-02 | 2.8 | 5.7E-1 |
