Skip to main content

Table 2 Analyses of temporal clustering of neuroblastic tumours at ages 0–24 years in the NRYPMDRa

From: Temporal clustering of neuroblastic tumours in children and young adults from Northern England

 

\( \widehat{\upbeta} \)b (SE)c

 

one-sided P-value d

Type of analysis

Within months

Within quarters

Within years

Within full study period

Between fortnightse

0.846 (0.310)

0.501 (0.108)

0.201 (0.051)

0.168 (0.044)

 

P = 0.004

P < 0.001

P < 0.001

P < 0.001

Between months

 

0.495 (0.165)

0.221 (0.073)

0.154 (0.062)

  

P = 0.002

P = 0.002

P = 0.008

Between quarters

  

0.201 (0.140)

0.020 (0.107)

   

P = 0.087

P = 0.39

Between years

   

−0.299 (0.216)

    

P = 0.92

  1. a)Based on cases diagnosed during 1968–2011 inclusive
  2. b)\( \widehat{\upbeta} \) is the one-step estimate of β, the extra-Poisson variation, calculated as S/i(0) in the notation of Muirhead [42]
  3. c)SE is the standard error of \( \widehat{\upbeta} \) in the absence of extra-Poisson variation, calculated as 1/√i(0) in the notation of Muirhead [42]
  4. d)P-values have been calculated using 10000 simulations, assuming Poisson variation. All P-values are one-sided
  5. e)Cases with a diagnosis date of the 15th of the month have been excluded from the analyses between fortnights but have been included in the other analyses
Back to article page

Environmental Health

ISSN: 1476-069X