Skip to main content

Table 3 Stratified analysis of associated SNPs by CNE and intensity of noise exposure

From: Associations of genetic variations in EYA4, GRHL2 and DFNA5 with noise-induced hearing loss in Chinese population: a case- control study

Exposure SNP Genotype Control Case P1 P2 OR (95 % CI)
CNE        
 <95 rs2521758 TT 244 209 0.040   1
  GT/GG 12 3 0.042a 0.115 (0.014, 0.921)a
 ≥95 TT 205 232   1
  GT/GG 9 10 0.587a 0.761 (0.284, 2.042)a
Intensity (dB)       
 <88 rs212769 GG 211 181 0.041   1
  AG/AA 72 71 0.503b 1.169 (0.740, 1.849)b
 ≥88 GG 143 155   1
  AG/AA 45 66 0.046b 1.727 (1.009, 2.954)b
  1. P1: P value of multiplicative interaction, which calculated by logistic model Multiplicative term; P2: P value of the association in each stratum
  2. acalculated with logistic regression adjusted by age, smoking, drinking
  3. bcalculated with logistic regression adjusted by age, smoking, drinking, years to noise exposure