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Table 5 Associations between ALT and POPs at baseline and at 12 months

From: Persistent organic pollutants and non-alcoholic fatty liver disease in morbidly obese patients: a cohort study

 

Baseline (n = 115)a

12 months (n = 92)b

Compound

B (95 % CI)

p-value

p-interactionc

B (95 % CI)

p-value

p-interactionc

HCB

-0.20 (-0.40,0.00)

0.055

0.220

0.09 (-0.09,0.28)

0.309

0.256

β-HCH

-0.17 (-0.33,-0.01)

0.035

0.070

0.18 (-0.02,0.39)

0.075

0.017

Trans-nonachlor

-0.11 (-0.26,0.04)

0.133

0.310

0.15 (0.00,0.30)

0.055

0.035

p,p′-DDE

-0.05 (-0.16,0.07)

0.446

0.759

0.11 (-0.01,0.24)

0.076

0.702

PCB - 118

-0.09 (-0.25,0.07)

0.275

0.414

0.19 (0.02,0.36)

0.032

0.074

PCB - 153

-0.21 (-0.42,-0.01)

0.043

0.567

0.18 (-0.02,0.38)

0.083

0.080

PCB - 138

-0.17 (-0.34,0.00)

0.052

0.576

0.14 (-0.05,0.33)

0.138

0.086

PCB - 156

-0.19 (-0.39,0.01)

0.065

0.683

0.19 (0.00,0.38)

0.047

0.053

PCB - 180

-0.30 (-0.56,-0.04)

0.023

0.832

0.20 (-0.01,0.41)

0.064

0.081

PCB - 170

-0.33 (-0.60,-0.06)

0.019

0.762

0.19 (-0.03,0.42)

0.093

0.093

BDE - 47

0.08 (-0.06,0.22)

0.260

0.866

0.07 (-0.07,0.20)

0.326

0.051

BDE - 153

0.11 (-0.02,0.23)

0.085

0.594

0.15 (0.04,0.26)

0.009

0.508

BDE - 209

-0.01 (-0.10,0.08)

0.801

0.705

0.02 (-0.08,0.11)

0.738

0.210

SumPCBs

-0.24 (-0.46,-0.02)

0.033

0.592

0.19 (-0.02,0.39)

0.078

0.071

SumBDEs

0.03 (-0.09,0.14)

0.662

0.580

0.07 (-0.05,0.19)

0.248

0.028

  1. aConcentrations of POPs (ng/g lipids) and ALT were log-transformed for the linear regression analysis at baseline that was adjusted for age, sex, BMI and fasting insulin
  2. bConcentrations of POPs (ng/g lipids) and ALT were log-transformed for the linear regression analysis at 12 months that was adjusted for age, sex, weight change and fasting insulin
  3. cp-value for interaction between each POP and sex was tested in a model where the POP*sex interaction term was added as a covariate in addition to other covariates used at baseline and at 12 months
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Environmental Health

ISSN: 1476-069X