Table 1 Estimation of user exposure to endotoxins from feed additives, including consideration of using filter mask FF P2 or FF P3 as preventative measure
From: Risks associated with endotoxins in feed additives produced by fermentation
Calculation | Identifier | Description | Amount | Source |
|---|---|---|---|---|
a | Endotoxin content IU/g product | |||
b | Dusting potential (g/m3) | |||
a × b | c | Endotoxin content in the air (IU/m3) | ||
d | No of premixture batches made/working day | 40 | EFSA Guidance on User Safety [35] | |
e | Time of exposure (s) per production of one batch | 20 | EFSA Guidance on User Safety [35] | |
d × e | f | Total duration of daily exposure/worker (s) | 800 | |
g | Uncertainty Factor | 2 | EFSA Guidance on User Safety [35] | |
f × g | h | Refined total duration of daily exposure/worker (s) | 1600 | |
h/3600 | i | Refined total duration of daily exposure (h) | 0.444 | |
j | Inhaled air (m3) per 8-h working day | 10 | EFSA Guidance on User Safety [35] | |
j/8 × i | k | Inhaled air during exposure (m3) | 0.556 | |
c × k | l | Endotoxin inhaled (IU) during exposure per 8-h working day | ||
m | Health based recommended exposure limit of endotoxin (IU/m3) per 8-h working day | 90 | Health Council of the Netherlands [29] | |
m × j | n | Health based recommended exposure limit of total endotoxin exposure (IU) per 8-h working day | 900 | |
l/10 | Endotoxins inhaled (IU) per 8 h working day reduced by filter mask FF P2 (reduction factor 10) | |||
l/20 | Endotoxins inhaled (IU) per 8 h working day reduced by filter mask FF P3 (reduction factor 20) |