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Table 3 Diseases and exposure-response relationships included in this assessment

From: Reducing burden of disease from residential indoor air exposures in Europe (HEALTHVENT project)

Exposuresa Health endpoints WHO RR PAF RR & PAF source(s) BoD calculationb
PM2.5 Asthma W113 1.009 f(RR, E)c Pope et al. 2002 [33] PAF(E, RR) × BoD2004
  Lung cancer W067 1.014 f(RR, E)c Pope et al. 2002 [33] PAF(E, RR) × BoD2004
  CV-diseases W104 1.009 f(RR, E)c Pope et al. 2002 [33] PAF(E, RR) × BoD2004
  COPD W112 1.009 f(RR, E)c Pope et al. 2002 [33] PAF(E, RR) × BoD2004
Outdoor bioaerosols Asthma W113 n/a 0.1d Jantunen et al., 2010 [22] PAF × BoD2004
VOC Asthma W113 n/a 0.05e Jantunen et al., 2010 [22] C/CEU × PAF × BoD2004
CO Acute toxication caused by carbon monoxide n/a n/a 0.9e Jantunen et al., 2010 [22] Cases x 20 years lost/case
Radon Lung cancer W067 1.0014 f(RR, E)c Darby et al., 2005 [34] PAF(E, RR) × BoD2004
Home dampness Respiratory infections W038 1.37 f(RR, E)c Fisk et al., 2007 [35] PAF(E, RR) × BoD2004
  Asthma W113 1.5 f(RR, E)c Fisk et al., 2007 [35] PAF(E, RR) × BoD2004
SHSf Lung cancer W067 1.21 f(RR, E)c US S.G. 2006 [36] PAF(E, RR) × BoD2004
  Ischaemic heart disease W107 1.27 f(RR, E)c US S.G. 2006 [36] PAF(E, RR) × BoD2004
  Asthma W113 1.97 f(RR, E)c Jaakkola et al., 2003 [37] PAF(E, RR) × BoD2004
  1. a)Population weighted average in EU26, b)C = National population weighted concentration, CEU = European average concentration, E = National population weighted exposure, c)Calculated as PAF = (f × (RR-1))/((f × (RR-1)) + 1), where RR = RR°E (see equation 4) [24], d)Original value of 0.25 in Jantunen et al. (2010) [22] adjusted to 0.1 due to separation of indoor and outdoor sources and focusing on pollen from outdoor air, e)Expert judgment PAF from the EnVIE panel used directly [21], see column PAF,
  2. f)Second hand smoke exposure of non-smoking adults at home.