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Table 3 Diseases and exposure-response relationships included in this assessment

From: Reducing burden of disease from residential indoor air exposures in Europe (HEALTHVENT project)

Exposuresa

Health endpoints

WHO

RR

PAF

RR & PAF source(s)

BoD calculationb

PM2.5

Asthma

W113

1.009

f(RR, E)c

Pope et al. 2002 [33]

PAF(E, RR) × BoD2004

 

Lung cancer

W067

1.014

f(RR, E)c

Pope et al. 2002 [33]

PAF(E, RR) × BoD2004

 

CV-diseases

W104

1.009

f(RR, E)c

Pope et al. 2002 [33]

PAF(E, RR) × BoD2004

 

COPD

W112

1.009

f(RR, E)c

Pope et al. 2002 [33]

PAF(E, RR) × BoD2004

Outdoor bioaerosols

Asthma

W113

n/a

0.1d

Jantunen et al., 2010 [22]

PAF × BoD2004

VOC

Asthma

W113

n/a

0.05e

Jantunen et al., 2010 [22]

C/CEU × PAF × BoD2004

CO

Acute toxication caused by carbon monoxide

n/a

n/a

0.9e

Jantunen et al., 2010 [22]

Cases x 20 years lost/case

Radon

Lung cancer

W067

1.0014

f(RR, E)c

Darby et al., 2005 [34]

PAF(E, RR) × BoD2004

Home dampness

Respiratory infections

W038

1.37

f(RR, E)c

Fisk et al., 2007 [35]

PAF(E, RR) × BoD2004

 

Asthma

W113

1.5

f(RR, E)c

Fisk et al., 2007 [35]

PAF(E, RR) × BoD2004

SHSf

Lung cancer

W067

1.21

f(RR, E)c

US S.G. 2006 [36]

PAF(E, RR) × BoD2004

 

Ischaemic heart disease

W107

1.27

f(RR, E)c

US S.G. 2006 [36]

PAF(E, RR) × BoD2004

 

Asthma

W113

1.97

f(RR, E)c

Jaakkola et al., 2003 [37]

PAF(E, RR) × BoD2004

  1. a)Population weighted average in EU26, b)C = National population weighted concentration, CEU = European average concentration, E = National population weighted exposure, c)Calculated as PAF = (f × (RR-1))/((f × (RR-1)) + 1), where RR = RR°E (see equation 4) [24], d)Original value of 0.25 in Jantunen et al. (2010) [22] adjusted to 0.1 due to separation of indoor and outdoor sources and focusing on pollen from outdoor air, e)Expert judgment PAF from the EnVIE panel used directly [21], see column PAF,
  2. f)Second hand smoke exposure of non-smoking adults at home.