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Table 7 Effect of interaction between blood lead and blood cadmium levels on odds of Hepatitis B seropositivity, NHANES 1999–2012

From: Elevated blood lead and cadmium levels associated with chronic infections among non-smokers in a cross-sectional analysis of NHANES data

Blood lead levels

Blood cadmium levels

<Median

≥Median

AOR (95 % CI) within Pb strata

N (Weighted %)

AOR (95 % CI)

N (Weighted %)

AOR (95 % CI)

<Median

4160 (2.2)

1.0

3622 (4.5)

1.51 (1.12–2.04)

1.42 (1.03–1.98)

P

P = 0.0310

≥Median

3011 (4.0)

1.23 (0.86–1.76)

6596 (7.9)

1.98 (1.51–2.61)

1.67 (1.23–2.25)

P = 0.2503

P = <0.0001

P = 0.0008

AOR (95 % CI) within Cd strata

 

1.12 (0.79–1.60)

 

1.35 (1.06–1.72)

 

P = 0.5209

P = 0.0155

  1. Measure of interaction on additive scale: RERI (95 % CI) = 0.24 (−0.28–0.76)
  2. Measure of interaction on multiplicative scale: ratio of ORs (95 % CI) = 1.07 (0.71–1.61); P = 0.7622
  3. AORs are adjusted for age, gender, race/ethnicity, country of birth origin, family income, self-reported general health condition, use of illicit/street injected drugs