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Table 1 Distribution of IL6 -572 G > C and IL6 -174 G > C genotypes and alleles by diabetes status

From: A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM10 exposure and diabetes

Genotype

Diabetes

No diabetes

N = 286

N = 5554

IL6 -572 G > C*

Genotype

 GG

248 (86.7)

4896 (88.2)

 GC

36 (12.6)

623 (11.2)

 CC

2 (0.7)

35 (0.6)

Allele

 G

532 (93)

10415 (93.7)

 C

40 (7)

693 (6.3)

IL6 -174 G > C**

Genotype

 GG

111 (39)

2081 (37)

 GC

135 (47)

2614 (47)

 CC

40 (14)

865 (16)

Allele

 G

357 (62)

6776 (61)

 C

215 (38)

4344 (39)

  1. Data are presented as absolute numbers (N) and relative numbers (%) in parentheses
  2. * P-value for Hardy-Weinberg Equilibrium (HWE) test in diabetes cases = 0.585; no diabetes = 0.006; overall = 0.006. P-value for Fisher’s exact test = 0.664
  3. ** P-value for Hardy-Weinberg Equilibrium test in diabetes cases = 0.918; no diabetes = 0.352; overall = 0.408. P-value of Chi-square test = 0.762
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Environmental Health

ISSN: 1476-069X