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Table 1 Distribution of IL6 -572 G > C and IL6 -174 G > C genotypes and alleles by diabetes status

From: A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM10 exposure and diabetes

Genotype Diabetes No diabetes
N = 286 N = 5554
IL6 -572 G > C*
Genotype
 GG 248 (86.7) 4896 (88.2)
 GC 36 (12.6) 623 (11.2)
 CC 2 (0.7) 35 (0.6)
Allele
 G 532 (93) 10415 (93.7)
 C 40 (7) 693 (6.3)
IL6 -174 G > C**
Genotype
 GG 111 (39) 2081 (37)
 GC 135 (47) 2614 (47)
 CC 40 (14) 865 (16)
Allele
 G 357 (62) 6776 (61)
 C 215 (38) 4344 (39)
  1. Data are presented as absolute numbers (N) and relative numbers (%) in parentheses
  2. * P-value for Hardy-Weinberg Equilibrium (HWE) test in diabetes cases = 0.585; no diabetes = 0.006; overall = 0.006. P-value for Fisher’s exact test = 0.664
  3. ** P-value for Hardy-Weinberg Equilibrium test in diabetes cases = 0.918; no diabetes = 0.352; overall = 0.408. P-value of Chi-square test = 0.762