Skip to main content

Table 5 Medians of PBDE levels (ng/g lipid) in studies which reported the association between birth weight and PBDEs

From: Maternal levels of endocrine disruptors, polybrominated diphenyl ethers, in early pregnancy are not associated with lower birth weight in the Canadian birth cohort GESTE

Country (ref)

N

Year (s)

Specimen analyzed

BDE-47

BDE-99

BDE-100

BDE-153

Covariates

Association birth weight/PBDEsa

Sweden (24)

254

1996 - 2010

Breast milk

1.30

0.26

0.25

0.54

Di-ortho PCB, gestational length, moternal age, pre-pregnancy BMI, weight gain during pregnancy, education, smoking and infant sex.

Negative

California, USA (21)

286

1999 - 2000

Maternal serum (2nd trimester of pregnancy)

14.57

3.85

2.45

2.03

Moternal age, marital status, parity, body mass index, country of birth (United States vs. other), family income, sex of infant

Negative

Taiwana (25)

20

2000 - 2001

Breast milk

1.52

0.51

0.37

0.87

Maternal age, pre-pregnancy BMI and parity.

BDE-47 geometric mean was higher for birth weight ≤ 3.05 Kg compared to birth weight > 3.05 Kg

Indiana, USA (5)

15

2001

Maternal serum (delivery)

28.00

5.70

4.20

2.90

-

No association

Ontario, Canada (22)

97

2004 - 2005

Maternal serum (24–28 WOA)

24.20

8.73

3.25

4.15

BMI, maternal age, parity, gestational age at birth, socio-economic status (family income and years of education), sex of the baby, and serum cotinine concentration.

Negative only for BDE-99

Australia (26)

150

2008 - 2011

Maternal plasma (38 WOA)

3.96

0.88

0.98

2.26

Maternal age, number of children, Gestational age, gender, Maternal BMI prior to pregnancy, maternal weight gain.

Negative not statistically significant

China (28)

215

2010 - 2012

Maternal serum (during pregnancy)

2.26

3.58

2.13

4.87

Maternal age, parity, education, pre-pregnancy BMI, weight gain during pregnancy, family income, gestational age

Positive association with PBDE-153 (in female infants only)

Spain (23)

473

2003 - 2008

Maternal serum (10–13 WOA)

< LOD

1.14

-

2.19

 

Negative only for BDE-99

486

Umbilical cord blood

1.73

1.05

-

1.91

-

North Carolina, USA (27)

137

2005 - 2008

Maternal serum (35–36 WOA)

18.87

5.5

4.61

5.65

Final models not show

No association

Our study

349

2007 - 2008

Maternal serum (<29 WOA)

20.93

4.03

2.21

4.21

Maternal age, marital status, BMI, infection, smoking status, PCBs, lead (ng/ml), plus previous pregnancies history (preterm infant and low birth weight infant) in multipara only (N = 234).

No association

  1. aMean
  2. WOA Weeks of amenorrhea