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Table 2 Fully-adjusted, survey-weighted associations between serum PBDE concentrations and having a current thyroid problem. Adjusted for: age, race/ethnicity, BMI, education, smoking, alcohol consumption, and current hormone use

From: PBDE flame retardants, thyroid disease, and menopausal status in U.S. women

  BDE47 n = 1075 BDE99 n = 1061 BDE100 n = 1089 BDE153 n = 1089 Sum BDEs n = 1061
  OR (95 % CI) OR (95 % CI) OR (95 % CI) OR (95 % CI) OR (95 % CI)
Men and Women Combined
Q1 + Q2 (ref) 1   1   1   1   1  
Q3 0.55 (0.20–1.49) 0.93 (0.38–2.27) 0.74 (0.44–1.25) 0.92 (0.30–2.84) 0.57 (0.23–1.39)
Q4 1.32 (0.90–1.96) 1.22 (0.80–1.84) 1.13 (0.79–1.60) 1.14 (0.56–2.31) 1.09 (0.71–1.67)
  BDE47 n = 512 BDE99 n = 504 BDE100 n = 518 BDE153 n = 518 Sum BDEs n = 504
All Women
Q1 + Q2 (ref) 1   1   1   1   1  
Q3 0.60 (0.19–1.85) 0.75 (0.27–2.08) 0.65 (0.27–1.54) 1.00 (0.27–3.78) 0.36** (0.15–0.89)
Q4 1.48** (1.05–2.09) 1.78** (1.16–2.75) 1.50* (0.97–2.31) 1.44 (0.68–3.05) 1.61** (1.10–2.36)
  BDE47 n = 236 BDE99 n = 233 BDE100 n = 240 BDE153 n = 240 Sum BDEs n = 233
Postmenopausal Women
Q1 + Q2 (ref) 1   1   1   1   1  
Q3 0.81 (0.24–2.71) 0.99 (0.34–2.93) 0.23** (0.07–0.68) 0.50 (0.13–1.90) 0.54 (0.15–1.97)
Q4 2.15* (0.86–5.37) 3.63** (1.12–11.8) 2.02* (0.93–4.36) 1.25 (0.49–3.21) 2.20* (0.92–5.26)
  1. ***p < 0.01,**p < 0.05, *p < 0.1