PBDE flame retardants, thyroid disease, and menopausal status in U.S. women

Table 3 Selected studies reporting associations between serum BDE 47 concentrations (ng/g lipid) and associations with thyroid hormone, in relation to NHANES serum concentrations

NHANES (all participants)	25th percentile 9.3			50th percentile 19.2				75th percentile 40.9
Epi Study	Hagmar 2001 [60]	Dallaire 2009 [59]	Bloom 2008 [58]	Chevrier 2010 [26]	Turyk 2008 [61]	Stapleton 2011 [29]	Abdelouahab 2013 [25]	Zota 2011 [30]
n	110	623	36	270	405	140	380	25
Gender	Men	Men	Men (mostly)	Women (pregnant)	Men	Women (pregnant)	Women (pregnant)	Women (pregnant)
Central Tendency BDE 47	1.04	2.16	7.9	15.3	16.2^#	16.5	21.5	43.1
TSH	-*	-	-	-*	-	+	+	+
Total T₃		+*			-*	+	-*
Free T₃					-	+	+
Total T₄				-	-	+*	-*	+
Free T₄		+	+	+	+	+*	+*	-

ISSN: 1476-069X