Fig. 1

Timeline of study procedures and time-varying data collection. ^aMean time between online screening and online consent was 9.5 ± 19.2 days (Range 0–163). ^bMean time between online consent and enrollment was 9.9 ± 11.7 days (Range 0–68). ^cMean time between enrollment visit and onset of fertile window was 9.8 ± 13.7 days (Range 0–76). ^dFirst day of fertile-quality cervical fluid observed by the woman marks the beginning of the fertile window. ^ePeak Day of fertility according to Peak Day Algorithm (last day of best quality cervical fluid in mid-cycle). ^fIf pregnancy occurred in Cycle 1, delivery estimated to take place at approximately the same time as Cycle 1 EDO/C + 38 weeks. If pregnancy occurred in Cycle 2, delivery estimated to take place at approximately the same time as Cycle 2 EDO/C + 38 weeks. ^gThese two questionnaires were added to the study protocol with IRB approval after recruitment began