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Table 2 The most uncertain parameters in the ERFs of chronic chlordecone effects

From: Public health and chronic low chlordecone exposures in Guadeloupe; Part 2: Health impacts, and benefits of prevention

Health outcome

Most uncertain parameter

Unit

Mean valuea

Low valuea

High valuea

Ratio high/low value

Liver cancer

CFi/b

(μg/kg/d)/(μg/L)

0.064

0.043

0.131

3.05

Prostate cancer

OR-1

(−)

0.77

0.21

1.58

7.52

Renal dysfunction

BMD10-HED

(mg/kg/d)−1

0.013

0.001

0.032

28.87

Cognitive development

IQ to ASQ equivalence

IQpt/ASQpt

1

0.2

2

10.00

  1. CFi/b: conversion factor of ingestion dose to blood concentration of chlordecone. OR-1: difference of risk in exposed and reference populations. IQ to ASQ equivalence: IQ equivalence of 1 point of fine motor skill score in Age and Stage Questionnaire
  2. aTaken from Part 1