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Table 4 Health impacts, annual costs and benefits from reducing chlordecone exposures in Guadeloupe (With threshold)

From: Public health and chronic low chlordecone exposures in Guadeloupe; Part 2: Health impacts, and benefits of prevention

Health outcome

Main source of variation

Population at risk

Period of exposure measurement

n

Fthr

Impact

CI low (€2006)

CI mean (€2006)

CI high (€2006)

Proportion (mean estimate)

Liver cancer

Conversion from ingestion dose to blood chlordecone

All

<2003

436 968

47 %

2.5

4 174 000

6 213 000

12 717 000

23 %

≥2003

458 465

29 %

0.6

951 000

1 415 000

2 896 000

11 %

Annual benefit

  

−2.0

3 223 000

4 798 000

9 821 000

35 %

Prostate cancer

IC95% of RR

Men > 44 years

<2003

72 566

64 %

1.8

896 000

3 286 000

6 742 000

12 %

≥2003

76 049

34 %

0.3

166 000

610 000

1 251 000

5 %

Annual benefit

  

−1.5

730 000

2 676 000

5 491 000

20 %

Renal dysfunction

BMD10-HED

Women

<2003

227 417

31 %

0.033

8 000

95 000

237 000

0.36 %

≥2003

239 470

24 %

0.011

3 000

31 000

77 000

0.24 %

Annual benefit

  

−0.022

5 000

64 000

160 000

0.47 %

Cognitive development

Equivalence between QI point and ASQ point

Male new born

<2003

3 747

86 %

1005.1

3 384 000

16 922 000

33 844 000

64 %

≥2003

3 929

64 %

652.4

2 155 000

10 779 000

21 557 000

84 %

Annual benefit

  

−352.7

1 229 000

6 143 000

12 287 000

45 %

Total

  

<2003

   

8 462 000

26 516 000

53 540 000

100 %

≥2003

   

3 275 000

12 835 000

25 781 000

100 %

Annual benefit

   

5 187 000

13 681 000

27 759 000

100 %

  1. n = population, 2002 census data for the first period of time and 2006 census data for second period. Fthr = fraction of collective exposure above threshold (for adults threshold = 0.5 μg/kg/d; for pregnant woman and effect on child development (cognitive) = 0.165 μg/kg/d). Impacts are expressed as number of deaths (mean estimate), except for cognitive development where the impacts are expressed in IQ point lost (mean estimate). CI = Cost of Impacts (= DALY * VOLY)
  2. Impact is the number of cases (Eq. 3), except IQ points for Cognitive development