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Table 4 Health impacts, annual costs and benefits from reducing chlordecone exposures in Guadeloupe (With threshold)

From: Public health and chronic low chlordecone exposures in Guadeloupe; Part 2: Health impacts, and benefits of prevention

Health outcome Main source of variation Population at risk Period of exposure measurement n Fthr Impact CI low (€2006) CI mean (€2006) CI high (€2006) Proportion (mean estimate)
Liver cancer Conversion from ingestion dose to blood chlordecone All <2003 436 968 47 % 2.5 4 174 000 6 213 000 12 717 000 23 %
≥2003 458 465 29 % 0.6 951 000 1 415 000 2 896 000 11 %
Annual benefit    −2.0 3 223 000 4 798 000 9 821 000 35 %
Prostate cancer IC95% of RR Men > 44 years <2003 72 566 64 % 1.8 896 000 3 286 000 6 742 000 12 %
≥2003 76 049 34 % 0.3 166 000 610 000 1 251 000 5 %
Annual benefit    −1.5 730 000 2 676 000 5 491 000 20 %
Renal dysfunction BMD10-HED Women <2003 227 417 31 % 0.033 8 000 95 000 237 000 0.36 %
≥2003 239 470 24 % 0.011 3 000 31 000 77 000 0.24 %
Annual benefit    −0.022 5 000 64 000 160 000 0.47 %
Cognitive development Equivalence between QI point and ASQ point Male new born <2003 3 747 86 % 1005.1 3 384 000 16 922 000 33 844 000 64 %
≥2003 3 929 64 % 652.4 2 155 000 10 779 000 21 557 000 84 %
Annual benefit    −352.7 1 229 000 6 143 000 12 287 000 45 %
Total    <2003     8 462 000 26 516 000 53 540 000 100 %
≥2003     3 275 000 12 835 000 25 781 000 100 %
Annual benefit     5 187 000 13 681 000 27 759 000 100 %
  1. n = population, 2002 census data for the first period of time and 2006 census data for second period. Fthr = fraction of collective exposure above threshold (for adults threshold = 0.5 μg/kg/d; for pregnant woman and effect on child development (cognitive) = 0.165 μg/kg/d). Impacts are expressed as number of deaths (mean estimate), except for cognitive development where the impacts are expressed in IQ point lost (mean estimate). CI = Cost of Impacts (= DALY * VOLY)
  2. Impact is the number of cases (Eq. 3), except IQ points for Cognitive development