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Table 2 Prostate cancer risk increase and ERF calculation (data from Multigner, 2010 [11])

From: Public health and chronic low chlordecone exposure in Guadeloupe, Part 1: hazards, exposure-response functions, and exposures

Exposure groups in the study (μg/Lblood) ORmultivar (IC95 %) (−) Delta OR (−) Averaged exposure (μg/Lblood) Delta Expo (μg/Lblood) ERF (μg/Lblood)−1
<0.25 (LD) 1 Ref. 0.125a Ref. Ref.
>0.25 to 0.47 1.11 (0.75-1.65) 0.11 0.360b 0.235 0.468
>0.47 to 0.96 1.22 (0.82-1.83) 0.22 0.716b 0.591 0.373
>0.96* 1.77 (1.21-2.58) 0.77 6.866 c 6.741 0.114
  1. ERF are calculated with Eq. 1
  2. Results in bold face are used to derive the ERF
  3. LD = limit of detection. Ref. = reference group
  4. Delta OR = OR - 1; delta expo = average exposure value – 0.125; ERF = delta OR/delta expo
  5. * The maximal value in the study is 49.1 μg/L (cf. Guldner 2011 [127])
  6. a = Value stated by Multignier et al. to compute the test for trend
  7. b = arithmetic mean of the minimum and maximum values of this exposure group
  8. c = geometric mean of the minimum and maximum values of this exposure group, respectively: 0.96 μg/L and 49.1 μg/L