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Table 2 Prostate cancer risk increase and ERF calculation (data from Multigner, 2010 [11])

From: Public health and chronic low chlordecone exposure in Guadeloupe, Part 1: hazards, exposure-response functions, and exposures

Exposure groups in the study (μg/Lblood)

ORmultivar (IC95 %) (−)

Delta OR (−)

Averaged exposure (μg/Lblood)

Delta Expo (μg/Lblood)

ERF (μg/Lblood)−1

<0.25 (LD)

1

Ref.

0.125a

Ref.

Ref.

>0.25 to 0.47

1.11 (0.75-1.65)

0.11

0.360b

0.235

0.468

>0.47 to 0.96

1.22 (0.82-1.83)

0.22

0.716b

0.591

0.373

>0.96*

1.77 (1.21-2.58)

0.77

6.866 c

6.741

0.114

  1. ERF are calculated with Eq. 1
  2. Results in bold face are used to derive the ERF
  3. LD = limit of detection. Ref. = reference group
  4. Delta OR = OR - 1; delta expo = average exposure value – 0.125; ERF = delta OR/delta expo
  5. * The maximal value in the study is 49.1 μg/L (cf. Guldner 2011 [127])
  6. a = Value stated by Multignier et al. to compute the test for trend
  7. b = arithmetic mean of the minimum and maximum values of this exposure group
  8. c = geometric mean of the minimum and maximum values of this exposure group, respectively: 0.96 μg/L and 49.1 μg/L