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Table 1 Characteristics of NBDPS hypospadias cases and controls with estimated atrazine exposure, 1998-2005

From: Hypospadias and maternal exposure to atrazine via drinking water in the National Birth Defects Prevention study

 

Cases

Controls

Characteristic

N

%

Missing

N

%

Missing

Demographic characteristics

      

State of residence **

  

0

  

0

 Arkansas

49

39.8

 

85

20.5

 

 Iowa

17

13.8

 

103

24.8

 

 Texas

8

6.5

 

101

24.3

 

 North Carolina

49

39.8

 

126

30.4

 

Maternal age

  

0

  

0

 <20

10

8.1

 

43

10.4

 

 20-24

27

22.0

 

89

21.5

 

 25-29

25

20.3

 

118

28.4

 

 30-34

42

34.2

 

105

25.3

 

 ≥35

19

15.5

 

60

14.5

 

Maternal race/ethnicity**

  

0

  

0

 Non-Hispanic white

94

76.4

 

242

58.3

 

 Non-Hispanic black

16

13.0

 

32

7.7

 

 Hispanic

8

6.5

 

106

25.5

 

 Other

5

4.1

 

35

8.4

 

Maternal education**

  

0

  

0

 <High school

5

4.1

 

86

20.7

 

 High school

30

24.4

 

111

26.8

 

 >High school

88

71.5

 

218

52.5

 

Previous pregnancies**

  

0

  

0

 No

55

44.7

 

122

29.4

 

 Yes

68

55.3

 

293

70.6

 

Plurality*

  

0

  

0

 Singleton birth

114

92.7

 

405

97.6

 

 Multiple birth

9

7.3

 

10

2.4

 

Behavioral characteristics

      

Private well use

  

2

  

9

 No

85

70.3

 

292

71.9

 

 Yes

36

29.7

 

114

28.1

 

Reported water consumption+

  

0

  

0

 0 glasses

3

2.4

 

22

5.3

 

 1-4 glasses

77

62.6

 

217

52.3

 

 5 or more glasses

43

35.0

 

176

42.4

 

Residential filtered tap water

  

2

  

9

 No

84

69.4

 

304

74.9

 

 Yes

37

30.6

 

102

25.1

 

Maternal choline intakea

  

0

  

0

 <187.4 mg

27

22.0

 

72

17.4

 

 187.4 – 249.6 mg

30

24.4

 

85

20.5

 

 249.7 – 336.3 mg

34

27.6

 

104

25.1

 

 >336.4 mg

32

26.0

 

154

37.1

 

Fertility medications or procedures*

  

0

  

4

 No

111

90.2

 

393

95.6

 

 Yes

12

9.8

 

18

4.4

 

Health characteristics

      

Diabetes

  

0

  

1

 No

115

93.5

 

374

90.3

 

 Yes

8

6.5

 

40

9.7

 

High blood pressure

  

0

  

0

 No

95

77.2

 

344

92.9

 

 Yes

28

22.8

 

71

17.1

 

Maternal BMI

  

1

  

22

 <18.5

6

4.9

 

20

5.1

 

 18.5-25

59

48.4

 

210

53.4

 

 25-30

25

20.5

 

84

21.4

 

 >30

32

26.2

 

79

20.1

 
  1. + p < 0.1
  2. *p < 0.05
  3. **p < 0.01
  4. aCategories for maternal choline intake from Carmichael et al. [14]