Gestational exposure to phthalates and gender-related play behaviors in 8-year-old children: an observational study

Table 4 Adjusted Associations of Gestational Urinary Phthalate Metabolite Concentrations with the PPPSI

Metabolites	Continuous Distribution						Dichotomized Distribution (<25th percentile vs. all others)^b
	Males			Females			Males			Females
	Estimate	95 % CI	p	Estimate	95 % CI	p	OR	95 % CI	p	OR	95 % CI	p
∑DEHP^a	−0.41	−1.12, 0.49	0.49	0.19	−0.80, 0.70	0.92	1.11	0.75–1.63	0.60	1.15	0.81–1.63	0.45
MEHP	−0.07	−0.8, 0.66	0.85	−0.03	−0.68, 0.62	0.93	0.95	0.66–1.37	0.77	1.09	0.81–1.47	0.58
MEHHP	−0.23	−1.00, 0.54	0.56	0.03	−0.67, 0.74	0.93	1.10	0.76–1.60	0.61	1.10	0.79–1.52	0.57
MEOHP	−0.28	−1.06, 0.5	0.48	0.02	−0.71, 0.74	0.96	1.13	0.77–1.654	0.54	1.12	0.80–1.56	0.52
MECPP	−0.37	−1.17, 0.43	0.37	−0.10	−0.90, 0.70	0.81	1.11	0.72–1.63	0.58	1.20	0.82–1.74	0.35
MCPP	−0.65	−1.81, 0.52	0.28	0.35	−0.98, 1.69	0.60	1.26	0.72–2.20	0.43	0.67	0.35–1.28	0.23
MBzP	−0.39	−1.21, 0.43	0.36	−0.22	−0.97, 0.52	0.56	1.39	0.91–2.11	0.13	1.26	0.88–1.81	0.20
MiBP	−0.55	−1.50, 0.41	0.27	0.15	−0.90, 1.21	0.78	1.69	1.00–2.86	0.049	0.68	0.41–1.14	0.15
MnBP	−0.41	−1.53, 0.71	0.49	0.19	−0.83, 1.20	0.72	1.44	0.82–2.53	0.21	1.01	0.63–1.62	0.96
MEP	0.28	−0.34, 0.9	0.38	0.55	−0.08, 1.18	0.09	0.72	0.51–1.02	0.07	0.70	0.51–0.970	0.03

All values are for each doubling of exposure, and adjusted for race and mother’s education. Bolded values are statistically significant at p <.05. Metabolite concentrations are the mean of the 16 and 26 week gestational urine samples and corrected for creatinine
^a∑DEHP expressed as MEHP, ng/mL (= molar sum of (MECPP, MEOHP, MEOHP, MEHP) in nmol/L *278/1000)
^b<25th percentile group has the least typical play behavior

ISSN: 1476-069X