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Table 5 Fecundability Ratio for In Utero Exposure to DDE, PCB, and Confounders, Karmaus Methoda

From: In utero exposure to polychlorinated biphenyls is associated with decreased fecundability in daughters of Michigan female fisheaters: a cohort study

 

All times of unprotected intercourse (n = 249)

TUIb ≥ 1 month (n = 207)

Women who planned a baby (n = 196)

Variable

FRe

95 % CI

FRe

95%CI

FRe

95%CI

Serum-DDE:c

 2.5–7.4 μg/L

1.61

0.90, 2.86

1.36

0.67, 2.76

1.62

0.88, 2.97

  > 7.4 μg/L

1.67

0.69, 4.07

1.35

0.42, 4.34

1.72

0.67, 4.43

Serum-PCB:c

 2.5–7.4 μg/L

0.60

0.36, 0.99

0.73

0.40, 1.33

0.50

0.28, 0.89

  > 7.4 μg/L

0.42

0.20, 0.88

0.58

0.20, 1.67

0.30

0.13, 0.68

Pelvic and genital infections before the TUI

1.00

0.62, 1.63

0.84

0.47, 1.49

1.02

0.59, 1.76

Smoking at the beginning of TUI

0.59

0.21, 1.64

0.43

0.13, 1.42

0.79

0.17, 3.63

Partner smoking at the beginning of TUI

2.09

1.20, 3.63

2.13

1.07, 4.25

1.96

0.90, 4.28

Alcohol consumption at the beginning of TUI (no. of drinks/day) d

 0.01–0.5

0.95

0.57, 1.59

1.01

0.55, 1.87

0.94

0.54, 1.63

  > 0.5

1.40

0.64, 3.09

0.94

0.32, 2.78

1.33

0.51, 3.44

Caffeine consumption at the beginning of TUI (mg/day) d

 100–300

0.72

0.43, 1.23

0.78

0.42, 1.44

0.74

0.40, 1.37

  > 300

0.91

0.54, 1.53

1.01

0.55, 1.89

0.68

0.34, 1.35

  1. aFemale Offspring of the Fisheater Family Health Study, 2000–2001
  2. bTUI-times of unprotected intercourse, leading or not leading to pregnancy
  3. cReference: <2.5 μg/L
  4. dReference: no
  5. eAdditionally controlling for age (14–20 years, 25–30 years, and 30 years and above) at the beginning of TUI, the birth cohorts
  6. (1943–1952, 1953–1962, 1963–1972, 1973–1982) and also Education (High school and less, Associate degree, College and above) as stratified variables