Table 2 eMS with PM2.5-associated methylation and association between corresponding transcript gene expression with PM2.5, ranked by gene expression association with PM2.5
| Â | Â | DNA Methylation | Gene Expression | ||||||
|---|---|---|---|---|---|---|---|---|---|
Genea | Chr | CpG | β (95% CI) | P-value | Adjusted P-value | Illumina Transcript | β (95% CI) | P-value | Adjusted P-value |
PM2.5 | |||||||||
ANKHD1 | 5 | cg20455854 | 0.139 (0.074, 0.203) | 2.77 × 10−5 | 0.034 | ILMN_1765091 | −0.048 (−0.074, −0.022) | 3.71 × 10−4 | 0.002 |
LGALS2 | 22 | cg07855639 | 0.081 (0.043, 0.120) | 3.28 × 10−5 | 0.034 | ILMN_1687306 | −0.147 (−0.240, −0.053) | 0.002 | 0.005 |
ANKRD11 | 16 | cg07598385 | 0.108 (0.056, 0.160) | 4.97 × 10−5 | 0.034 | ILMN_2108709 | −0.075 (−0.142, −0.008) | 0.028 | 0.046 |
BAZ2B | 2 | cg17360854 | 0.081 (0.042, 0.120) | 5.08 × 10−5 | 0.034 | ILMN_1720850 | −0.016 (−0.060, 0.027) | 0.463 | 0.578 |
PPIE | 1 | cg23599683 | −0.057 (−0.085, −0.029) | 7.17 × 10−5 | 0.039 | ILMN_1680341 | 0.004 (−0.020, 0.028) | 0.728 | 0.728 |