Variable
|
OP (n = 42)
| |
PL (n = 42)
| |
P value*
|
---|
Baseline
|
Follow up
|
Baseline
|
Follow up
|
---|
PchE activity (U/mL)
|
Mean (SD)
|
1.58 (0.41)
|
1.60 (0.40)
|
1.58 (0.42)
|
1.60 (0.41)
|
0.775a
|
Symptoms
|
Sum of all symptoms
|
42
|
41
|
31
|
40
|
0.378b
|
Number of symptoms per farmer, n (%)
|
0
|
22 (52.4)
|
23 (54.8)
|
27 (64.3)
|
21 (50.0)
| |
1
|
11 (26.2)
|
10 (23.8)
|
6 (14.3)
|
10 (23.8)
| |
2
|
5 (11.9)
|
3 (7.1)
|
6 (14.3)
|
5 (11.9)
| |
≥ 3
|
4 (9.5)
|
6 (14.3)
|
3 (7.1)
|
6 (14.3)
| |
Distribution, n (%)
|
Headache
|
6 (14.3)
|
10 (23.8)
|
4 (9.5)
|
10 (23.8)
| |
Dizziness
|
1 (2.4)
|
1 (2.4)
|
2 (4.8)
|
6 (14.3)
| |
Skin irritation
|
7 (16.7)
|
9 (21.4)
|
3 (7.1)
|
10 (23.8)
| |
Extreme tiredness
|
4 (9.5)
|
5 (11.9)
|
6 (14.3)
|
5 (11.9)
| |
Weakness
|
6 (14.3)
|
3 (7.1)
|
4 (9.5)
|
2 (4.8)
| |
Anxiety
|
3 (7.1)
|
1 (2.4)
|
0 (0.0)
|
1 (2.4)
| |
Excessive sweating
|
5 (11.9)
|
4 (9.5)
|
1 (2.4)
|
0 (0.0)
| |
Trembling hands
|
1 (2.4)
|
1 (2.4)
|
1 (2.4)
|
1 (2.4)
| |
Vomiting
|
0 (0.0)
|
0 (0.0)
|
1 (2.4)
|
0 (0.0)
| |
Diarrhea
|
0 (0.0)
|
0 (0.0)
|
0 (0.0)
|
0 (0.0)
| |
Abdominal pain
|
1 (2.4)
|
2 (4.8)
|
1 (2.4)
|
1 (2.4)
| |
Blurred vision
|
4 (9.5)
|
1 (2.4)
|
3 (7.1)
|
4 (9.5)
| |
Paralysis
|
0 (0.0)
|
0 (0.0)
|
0 (0.0)
|
0 (0.0)
| |
Salivation
|
1 (2.4)
|
1 (2.4)
|
1 (2.4)
|
0 (0.0)
| |
Tearing
|
0 (0.0)
|
0 (0.0)
|
2 (4.8)
|
0 (0.0)
| |
Lack of coordination
|
0 (0.0)
|
1 (2.4)
|
0 (0.0)
|
0 (0.0)
| |
Respiratory difficulties
|
3 (7.1)
|
2 (4.8)
|
2 (4.8)
|
0 (0.0)
| |
Confusion
|
0 (0.0)
|
0 (0.0)
|
0 (0.0)
|
0 (0.0)
| |
- * = For difference between the organophosphate spray session and the placebo spray session
-
a = Two sample t-test
-
b = Mann Whitney U-test