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Table 4 Results of the outcome measures for the organophosphate spray session (OP) and the placebo spray session (PL)

From: The use of self-reported symptoms as a proxy for acute organophosphate poisoning after exposure to chlorpyrifos 50% plus cypermethrin 5% among Nepali farmers: a randomized, double-blind, placebo-controlled, crossover study

Variable OP (n = 42)   PL (n = 42)   P value*
Baseline Follow up Baseline Follow up
PchE activity (U/mL)
 Mean (SD) 1.58 (0.41) 1.60 (0.40) 1.58 (0.42) 1.60 (0.41) 0.775a
Symptoms
 Sum of all symptoms 42 41 31 40 0.378b
Number of symptoms per farmer, n (%)
 0 22 (52.4) 23 (54.8) 27 (64.3) 21 (50.0)  
 1 11 (26.2) 10 (23.8) 6 (14.3) 10 (23.8)  
 2 5 (11.9) 3 (7.1) 6 (14.3) 5 (11.9)  
  ≥ 3 4 (9.5) 6 (14.3) 3 (7.1) 6 (14.3)  
Distribution, n (%)
 Headache 6 (14.3) 10 (23.8) 4 (9.5) 10 (23.8)  
 Dizziness 1 (2.4) 1 (2.4) 2 (4.8) 6 (14.3)  
 Skin irritation 7 (16.7) 9 (21.4) 3 (7.1) 10 (23.8)  
 Extreme tiredness 4 (9.5) 5 (11.9) 6 (14.3) 5 (11.9)  
 Weakness 6 (14.3) 3 (7.1) 4 (9.5) 2 (4.8)  
 Anxiety 3 (7.1) 1 (2.4) 0 (0.0) 1 (2.4)  
 Excessive sweating 5 (11.9) 4 (9.5) 1 (2.4) 0 (0.0)  
 Trembling hands 1 (2.4) 1 (2.4) 1 (2.4) 1 (2.4)  
 Vomiting 0 (0.0) 0 (0.0) 1 (2.4) 0 (0.0)  
 Diarrhea 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)  
 Abdominal pain 1 (2.4) 2 (4.8) 1 (2.4) 1 (2.4)  
 Blurred vision 4 (9.5) 1 (2.4) 3 (7.1) 4 (9.5)  
 Paralysis 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)  
 Salivation 1 (2.4) 1 (2.4) 1 (2.4) 0 (0.0)  
 Tearing 0 (0.0) 0 (0.0) 2 (4.8) 0 (0.0)  
 Lack of coordination 0 (0.0) 1 (2.4) 0 (0.0) 0 (0.0)  
 Respiratory difficulties 3 (7.1) 2 (4.8) 2 (4.8) 0 (0.0)  
 Confusion 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)  
  1. * = For difference between the organophosphate spray session and the placebo spray session
  2. a = Two sample t-test
  3. b = Mann Whitney U-test