Skip to main content

Table 4 Results of the outcome measures for the organophosphate spray session (OP) and the placebo spray session (PL)

From: The use of self-reported symptoms as a proxy for acute organophosphate poisoning after exposure to chlorpyrifos 50% plus cypermethrin 5% among Nepali farmers: a randomized, double-blind, placebo-controlled, crossover study

Variable

OP (n = 42)

 

PL (n = 42)

 

P value*

Baseline

Follow up

Baseline

Follow up

PchE activity (U/mL)

 Mean (SD)

1.58 (0.41)

1.60 (0.40)

1.58 (0.42)

1.60 (0.41)

0.775a

Symptoms

 Sum of all symptoms

42

41

31

40

0.378b

Number of symptoms per farmer, n (%)

 0

22 (52.4)

23 (54.8)

27 (64.3)

21 (50.0)

 

 1

11 (26.2)

10 (23.8)

6 (14.3)

10 (23.8)

 

 2

5 (11.9)

3 (7.1)

6 (14.3)

5 (11.9)

 

  ≥ 3

4 (9.5)

6 (14.3)

3 (7.1)

6 (14.3)

 

Distribution, n (%)

 Headache

6 (14.3)

10 (23.8)

4 (9.5)

10 (23.8)

 

 Dizziness

1 (2.4)

1 (2.4)

2 (4.8)

6 (14.3)

 

 Skin irritation

7 (16.7)

9 (21.4)

3 (7.1)

10 (23.8)

 

 Extreme tiredness

4 (9.5)

5 (11.9)

6 (14.3)

5 (11.9)

 

 Weakness

6 (14.3)

3 (7.1)

4 (9.5)

2 (4.8)

 

 Anxiety

3 (7.1)

1 (2.4)

0 (0.0)

1 (2.4)

 

 Excessive sweating

5 (11.9)

4 (9.5)

1 (2.4)

0 (0.0)

 

 Trembling hands

1 (2.4)

1 (2.4)

1 (2.4)

1 (2.4)

 

 Vomiting

0 (0.0)

0 (0.0)

1 (2.4)

0 (0.0)

 

 Diarrhea

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 

 Abdominal pain

1 (2.4)

2 (4.8)

1 (2.4)

1 (2.4)

 

 Blurred vision

4 (9.5)

1 (2.4)

3 (7.1)

4 (9.5)

 

 Paralysis

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 

 Salivation

1 (2.4)

1 (2.4)

1 (2.4)

0 (0.0)

 

 Tearing

0 (0.0)

0 (0.0)

2 (4.8)

0 (0.0)

 

 Lack of coordination

0 (0.0)

1 (2.4)

0 (0.0)

0 (0.0)

 

 Respiratory difficulties

3 (7.1)

2 (4.8)

2 (4.8)

0 (0.0)

 

 Confusion

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 
  1. * = For difference between the organophosphate spray session and the placebo spray session
  2. a = Two sample t-test
  3. b = Mann Whitney U-test