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Table 3 Standardized path coefficients depicting the relationship between 5 chemicals, cognitive functioning and covariates for all participants NHANES 1999–2002 (N = 498)

From: A path analysis of multiple neurotoxic chemicals and cognitive functioning in older US adults (NHANES 1999–2002)

Path Path coefficient (95% CI) p-value
  Lipid-adjusted Non-lipid-adjusted Lipid-adjusted Non-lipid-adjusted
PCB 74 → DSC 0.00 (−0.13, 0.13) −0.001 (−0.14, 0.13) 0.99 0.99
PCB 118 → DSC −0.06 (−0.20, 0.08) −0.06 (−0.22, 0.09) 0.41 0.41
PCB 146 → DSC −0.16 (−0.29, −0.02) −0.17 (−0.32, −0.02) 0.02 0.03
PCB 153 → DSC 0.20 (0.05, 0.35) 0.21 (0.06, 0.37) 0.01 0.008
Lead → DSC −0.10 (−0.20, −0.006) −0.10 (−0.20, −0.007) 0.04 0.04
aPIR2 → DSC 0.18 (0.06, 0.30) 0.18 (0.06, 0.30) 0.003 0.003
bPIR3 → DSC 0.28 (0.16, 0.41) 0.29 (0.16, 0.41) <0.001 <0.001
cED2 → DSC 0.24 (0.16, 0.32) 0.26 (0.17, 0.34) <0.001 <0.001
dED3 → DSC 0.30 (0.22, 0.38) 0.24 (0.16, 0.32) <0.001 <0.001
eED4 → DSC 0.39 (0.27, 0.52) 0.30 (0.22, 0.38) <0.001 <0.001
fMA → DSC −0.11 (−0.16, −0.06) −0.11 (−0.16, −0.06) <0.001 <0.001
gOH → DSC −0.14 (−0.23, −0.06) −0.14 (−0.23, −0.06) 0.001 0.001
hNHB → DSC −0.16 (−0.23, −0.10) −0.16 (−0.22, −0.10) <0.001 <0.001
Age → DSC −0.31 (−0.39, −0.24) −0.31 (−0.39, −0.24) <0.001 <0.001
Sex → DSC 0.12 (0.03, 0.20) 0.12 (0.03, 0.10) 0.007 0.007
Smoke → DSC −0.01 (−0.12, 0.09) −0.01 (−0.12, 0.10) 0.85 0.85
  1. a PIR2 2nd Tertile Poverty Index Ratio
  2. b PIR2 3 nd Tertile Poverty Index Ratio
  3. c Ed2 High School Grad/GED
  4. d Ed3 Some College or AA degree
  5. e Ed4 College Graduate or above
  6. f MA Mexican American
  7. g OH Other Hispanic
  8. h NHB Non-Hispanic Black