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Table 3 Standardized path coefficients depicting the relationship between 5 chemicals, cognitive functioning and covariates for all participants NHANES 1999–2002 (N = 498)

From: A path analysis of multiple neurotoxic chemicals and cognitive functioning in older US adults (NHANES 1999–2002)

Path

Path coefficient (95% CI)

p-value

 

Lipid-adjusted

Non-lipid-adjusted

Lipid-adjusted

Non-lipid-adjusted

PCB 74 → DSC

0.00 (−0.13, 0.13)

−0.001 (−0.14, 0.13)

0.99

0.99

PCB 118 → DSC

−0.06 (−0.20, 0.08)

−0.06 (−0.22, 0.09)

0.41

0.41

PCB 146 → DSC

−0.16 (−0.29, −0.02)

−0.17 (−0.32, −0.02)

0.02

0.03

PCB 153 → DSC

0.20 (0.05, 0.35)

0.21 (0.06, 0.37)

0.01

0.008

Lead → DSC

−0.10 (−0.20, −0.006)

−0.10 (−0.20, −0.007)

0.04

0.04

aPIR2 → DSC

0.18 (0.06, 0.30)

0.18 (0.06, 0.30)

0.003

0.003

bPIR3 → DSC

0.28 (0.16, 0.41)

0.29 (0.16, 0.41)

<0.001

<0.001

cED2 → DSC

0.24 (0.16, 0.32)

0.26 (0.17, 0.34)

<0.001

<0.001

dED3 → DSC

0.30 (0.22, 0.38)

0.24 (0.16, 0.32)

<0.001

<0.001

eED4 → DSC

0.39 (0.27, 0.52)

0.30 (0.22, 0.38)

<0.001

<0.001

fMA → DSC

−0.11 (−0.16, −0.06)

−0.11 (−0.16, −0.06)

<0.001

<0.001

gOH → DSC

−0.14 (−0.23, −0.06)

−0.14 (−0.23, −0.06)

0.001

0.001

hNHB → DSC

−0.16 (−0.23, −0.10)

−0.16 (−0.22, −0.10)

<0.001

<0.001

Age → DSC

−0.31 (−0.39, −0.24)

−0.31 (−0.39, −0.24)

<0.001

<0.001

Sex → DSC

0.12 (0.03, 0.20)

0.12 (0.03, 0.10)

0.007

0.007

Smoke → DSC

−0.01 (−0.12, 0.09)

−0.01 (−0.12, 0.10)

0.85

0.85

  1. a PIR2 2nd Tertile Poverty Index Ratio
  2. b PIR2 3 nd Tertile Poverty Index Ratio
  3. c Ed2 High School Grad/GED
  4. d Ed3 Some College or AA degree
  5. e Ed4 College Graduate or above
  6. f MA Mexican American
  7. g OH Other Hispanic
  8. h NHB Non-Hispanic Black