Skip to main content

Table 5 Standardized path coefficients depicting the relationship between 5 chemicals, cognitive functioning and covariates for females and males age years old, NHANES 1999-2002

From: A path analysis of multiple neurotoxic chemicals and cognitive functioning in older US adults (NHANES 1999–2002)

Path Path coefficient (95% CI) p-value    
  Lipid-adjusted Non-lipid-adjusted Lipid-adjusted Non-lipid-adjusted
Males (N = 231)
PCB 74 → DSC 0.03 (−0.11, 0.17) 0.03 (−0.13, 0.18) 0.66 0.74
PCB 118 → DSC −0.01 (−0.25, 0.22) −0.002 (−0.26, 0.26) 0.92 0.99
PCB 146 → DSC −0.09 (−0.31, 0.13) −0.11 (−0.36, 0.14) 0.42 0.38
PCB 153 → DSC 0.05 (−0.22, 0.32) 0.05 (−0.25, 0.35) 0.72 0.74
Lead → DSC −0.09 (−0.24, 0.06) −0.09 (−0.23, 0.06) 0.23 0.23
aPIR2 → DSC 0.21 (0.05, 0.36) 0.21 (0.06, 0.36) 0.01 0.008
bPIR3 → DSC 0.39 (0.21, 0.58) 0.39 (0.21, 0.58) <0.001 <0.001
cED2 → DSC 0.20 (0.10, 0.30) 0.20 (0.11, 0.30) <0.001 <0.001
dED3 → DSC 0.25 (0.15, 0.36) 0.25 (0.14, 0.36) <0.001 <0.001
eED4 → DSC 0.35 (0.20, 0.50) 0.35 (0.20, 0.50) <0.001 <0.001
fMA → DSC −0.10 (−0.16, −0.03) −0.10 (−0.16, −0.03) 0.003 0.002
gOH → DSC −0.17 (−0.35, 0.02) −0.17 (−0.36, 0.02) 0.09 0.08
hNHB → DSC −0.14 (−0.23, −0.05) −0.14 (−0.23, −0.05) 0.003 0.002
Age → DSC −0.27 (−0.36, −0.18) −0.27 (−0.36, −0.18) <0.001 <0.001
Smoke → DSC 0.05 (−0.10, 0.20) 0.05 (−0.10, 0.21) 0.51 0.51
Females (N = 267)
PCB 74 → DSC 0.005 (−0.25, 0.26) 0.008 (−0.24, 0.26) 0.97 0.95
PCB 118 → DSC −0.12 (−0.32, 0.08) −0.12 (−0.33, 0.08) 0.25 0.24
PCB 146 → DSC −0.21 (−0.45, 0.03) −0.22 (−0.46, 0.03) 0.08 0.08
PCB 153 → DSC 0.32 (0.05, 0.59) 0.33 (0.05, 0.61) 0.02 0.02
Lead → DSC −0.12 (−0.26, 0.01) −0.12 (−0.26, 0.01) 0.08 0.05
PIR2 → DSC 0.15 (0.000, 0.31) 0.16 (0.002, 0.31) 0.05 <0.001
PIR3 → DSC 0.19 (0.03, 0.34) 0.19 (0.03, 0.34) 0.02 0.0001
ED2 → DSC 0.28 (0.15, 0.41) 0.28 (0.15, 0.41) <0.001 <0.0001
ED3 → DSC 0.23 (0.09, 0.36) 0.23 (0.09, 0.36) 0.001 <0.001
ED4 → DSC 0.22 (0.11, 0.33) 0.22 (0.11, 0.33) <0.001 0.02
MA → DSC −0.13 (−0.19, −0.06) −0.13 (−0.19, −0.06) <0.001 <0.001
OH → DSC −0.15 (−0.27, −0.03) −0.15 (−0.27, −0.03) 0.02 0.11
NHB → DSC −0.19 (−0.27, −0.11) −0.19 (−0.27, −0.11) <0.001 <0.001
Age → DSC −0.37 (−0.48, −0.25) −0.37 (−0.49, −0.25) <0.001 <0.001
Smoke → DSC −0.08 (−0.22, 0.06) −0.08 (−0.22, 0.06) 0.28 0.28
  1. a PIR2 2nd Tertile Poverty Index Ratio
  2. b PIR3 3nd Tertile Poverty Index Ratio
  3. c Ed2 High School Grad/GED
  4. d Ed3 Some College or AA degree
  5. e Ed4 College Graduate or above
  6. f MA Mexican American
  7. g OH Other Hispanic
  8. h NHB Non-Hispanic Black