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Table 4 Tests and measures of mediation for MDA in the relationship between mercury and liver function

From: Blood mercury concentrations are associated with decline in liver function in an elderly population: a panel study

Mediation variable

Outcome

Indirect effect

S.E

P value for Sobel test

Percent (%) of the total effect that is mediated

All participants

 MDA

AST

1.0× 10−5

6.3× 10−5

0.872

11.92

ALT

−1.2× 10−5

7.3× 10−5

0.873

12.17

GGT

1.0× 10−5

6.6× 10−5

0.879

19.38

Non-drinkers

 MDA

AST

1.1× 10−4

3.2× 10−4

0.735

3.24

ALT

−2.2× 10−4

4.1× 10−4

0.583

7.37

GGT

1.2× 10−5

3.3 × 10−4

0.971

27.29

  1. Abbreviations: ALT Alanine transaminase, AST aspartate aminotransferase, BMI body mass index, CI confidence interval, GGT Gamma-glutamyl transferase, MDA Malondialdehyde, S.E standard error