Fig. 1From: The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expressionMultiple developmental genes are associated with expression of AQP9 in fetal placental tissue. Multivariable linear regression analyses were performed to determine the association of placental AQP9 expression with placental developmental/stemness gene expression, for (a) female, and (b) male fetal placenta. The analyses were adjusted for maternal age. GLI1/GLI1-2 and PTCH1/PTCH1-2 are sequence-distinct NanoString probes designed to measure the expression of GLI1 and PTCH1. Dots depict coefficient estimates and error bars represent 95% CIs. Significant associations are those with 95% CIs not crossing zero (dotted line) and are marked by asterisks (* PÂ <Â 0.05, **PÂ <Â 0.01, ***PÂ <Â 0.001). c Venn diagram summarizing AQP9-associated genes in males and female placenta. Green; HH pathway-related genes, purple; NOTCH pathway-related genes, blue; WNT pathway-related genes, orange; stemness genesBack to article page