Serum levels of environmental pollutants is a risk factor for breast cancer in Inuit: a case control study

Table 6 Serum levels of PFAA (ng/ml) in breast cancer cases and controls

Parameters	% > DL	Cases				Controls				p-value ^a	age adjusted p-value ^b
		n	median	P25-P75	Min-max	n	median	P25-P75	Min-max		age adjusted p-value ^b
∑PFAA		77	48.90	21.60–95.49	7.22–283.68	81	27.91	14.56–63.62	2.96–160.56	0.001	0.020
∑PFCA		77	8.55	5.66–17.72	2.20–72.93	81	6.97	3.51–17.06	0.96–49.71	0.016	0.225
PFHpA	72.1	77	0.11	0.05–0.30	0.03–1.55	81	0.08	0.05–0.18	0.03–0.59	0.022	0.170
PFOA	96.9	77	2.08	1.33–2.91	0.20–9.52	81	1.48	0.90–2.40	0.20–6.29	0.009	0.139
PFNA	96.3	77	3.28	1.45–4.97	0.30–38.60	81	1.83	0.76–4.63	0.25–12.50	0.055	0.530
PFDA	99.4	77	1.30	0.80–2.90	0.20–11.10	81	1.01	0.43–2.52	0.05–6.41	0.015	0.177
PFUnA	98.1	77	2.23	1.63–5.09	0.20–24.90	81	2.02	0.90–4.66	0.03–20.0	0.026	0.253
PFDoA	57.1	77	0.40	0.21–0.73	0.15–5.71	81	0.21	0.21–0.88	0.15–6.49	0.496	0.719
∑PFSA		77	38.10	14.80–68.11	5.02–211.00	81	19.91	10.02–44.35	2.00–142.26	0.001	0.014
PFHxS	98.8	77	2.52	0.96–4.07	0.19–23.40	81	1.14	0.64–2.91	0.16–13.90	0.002	0.031
PFOS	100.0	77	35.50	13.45–62.75	4.23–187.00	81	18.2	8.99–41.40	1.70–133.00	0.001	0.015

% > DL: % of samples above decetion limet; n: number of observations per group; P25-P75: 25 percentile – 75 percentile; ^a p-value for the difference between cases and controls tested on ln-transformed variables with independent samples t-test; ^b p-value for the difference between cases and controls when adjusting for age, tested with ANCOVA test with age as a covariate factor; Bold text: significant finding; ∑PFCA: PFHpA, PFOA, PFNA, PFDA, PFUnA, PFDoA and PFTrA; ∑PFSA: PFHxS, PFOS and PFOSA; ∑PFAA: ∑PFCA + ∑PFSA. The serum concentration of PFAA was measured in ng/ml

ISSN: 1476-069X