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Table 7 Serum levels of PFAA in cases and controls in the two recruitment periods

From: Serum levels of environmental pollutants is a risk factor for breast cancer in Inuit: a case control study

Parameters

2000–2003

2011–2014

P-value a

P-value b

P-value c

 

Median serum levels

Median serum levels

all

cases

controls

 

All

Cases

Controls

All

Cases

Controls

   

∑PFAA

49.11

55.30

25.65

27.91

31.18

27.91

0.159

0.007

0.669

∑PFCA

6.59

7.95

4.78

9.08

9.83

8.75

0.001

0.051

0.003

 PFHpA

0.05

0.05

0.05

0.14

0.17

0.13

0.006

0.084

0.012

 PFOA

2.27

2.50

1.62

1.49

1.68

1.45

0.419

0.074

0.558

 PFNA

1.50

1.80

0.89

2.64

3.03

2.58

<0.001

0.001

<0.001

 PFDA

0.96

1.20

0.49

1.34

1.34

1.34

<0.001

0.022

0.001

 PFUnA

1.80

2.00

0.98

2.49

2.58

2.35

0.001

0.029

0.003

 PFDoA

0.15

0.20

0.15

0.54

0.56

0.48

<0.001

<0.001

<0.001

∑PFSA

42.80

48.20

20.71

19.90

21.39

19.90

0.010

<0.001

0.818

 PFHxS

2.84

3.50

1.38

1.11

1.47

1.08

<0.001

<0.001

0.158

 PFOS

39.70

45.60

18.06

18.20

19.35

18.20

0.009

<0.001

0.796

  1. The differences between the two recruitment periods were tested with independent samples t-test. aThe p-value form independent samples t-test on ln-transformed variables between all the participants; bThe p-value from independent samples t-test on ln-transformed variables between the cases; cThe p-value from independent samples t-test on ln-transformed variables between the controls; Bold text: significant finding; ∑PFCA: PFHpA, PFOA, PFNA, PFDA, PFUnA, PFDoA and PFTrA; ∑PFSA: PFHxS, PFOS and PFOSA; ∑PFAA: ∑PFCA + ∑PFSA. The serum concentration of PFAS was measured in ng/ml
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Environmental Health

ISSN: 1476-069X