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Table 4 Relationships between IQR increases in estimated intercepts and slopes of exposure across in utero development and hormone levels at 8–14 years (n = 104)a

From: Impact of phthalate and BPA exposure during in utero windows of susceptibility on reproductive hormones and sexual maturation in peripubertal males

  Estradiol Testosterone SHBG DHEA-S Inhibin B
%Δ/IQR (95% CI) %Δ/IQR (95% CI) %Δ/IQR (95% CI) %Δ/IQR (95% CI) %Δ/IQR (95% CI)
BPAb Intercept −3.6 (−13.6, 7.5) 12.8 (−16, 51.6) 2.3 (−8.8, 14.9) −0.9 (−15.1, 15.7) 5.7 (−6.1, 18.9)
Slope n/a n/a n/a n/a n/a
MBzPb Intercept 6.1 (−4.5, 17.9) 20.4 (−9.5, 60.1) 9.8 (−1.7, 22.6) −5.4 (−18.5, 9.9) 1.5 (−9.6, 13.8)
Slope n/a n/a n/a n/a n/a
MCPP Intercept 8.3 (−5.3, 24.0) 9.4 (−24.2, 57.8) 15.3 (0.3, 32.6)* −7.1 (−23.2, 12.5) 5.6 (−8.7, 22.3)
Slope 2.7 (−9.7, 16.9) −0.5 (−30.0, 41.3) 14.5 (0.2, 30.9)* −7.3 (−22.8, 11.4) −1.4 (−14.3, 13.3)
MEP Intercept −6.3 (−17.2, 6.1) 6.7 (−23.5, 48.8) 4.9 (−8.1, 19.7) −6.7 (−21.8, 11.3) −6.8 (−18.3, 6.4)
Slope −7.4 (−16.8, 3.1) −22.1 (−41.6, 3.8) 0.0 (−10.8, 12.1) −4.8 (−18.3, 10.9) −12.9 (−22.3, −2.4)*
ΣDEHP Intercept 15.0 (3.2, 28.2)* 6.2 (−21.6, 43.9) 9.4 (−2.8, 23.0) 0.4 (−14.4, 17.7) 6.6 (−5.4, 20.2)
Slope 0.9 (−9.7, 12.8) −9.1 (−33.3, 24.0) 9.2 (−3.2, 23.0) −2.2 (−16.8, 15.1) −6.6 (−17.3, 5.6)
ΣDBP Intercept 8.7 (−7.0, 27.1) −12.4 (−42.6, 33.7) 11.2 (−5.7, 31.1) −14.9 (−31.7, 5.9) 5.1 (−11.3, 24.5)
Slope 0.7 (−12.1, 15.2) −19.8 (−44.4, 15.7) 10.5 (−4.2, 27.4) −14.4 (−29.2, 3.6) −2.7 (−15.9, 12.7)
  1. *p < 0.05
  2. aAdjusted for child age and BMI z-score. bIntercept and slope highly correlated (BPA r = −0.82, MBzP r = −0.99), only intercept included in model