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Table 5 Association between head and neck cancer and exclusive exposure to combinations of chlorinated solvents

From: Occupational exposure to chlorinated solvents and risk of head and neck cancer in men: a population-based case-control study in France

   

Head and neck

Oral cavity

Oropharynx

Hypopharynx

Oral cavity

/pharynx NOS

Larynx

   

n = 1693

n = 326

n = 497

n = 336

n = 114

n = 420

 

Co

Ca

ORa

[95%CI]

Ca

ORa

[95%CI]

Ca

ORa

[95%CI]

Ca

ORa

[95%CI]

Ca

ORa

[95%CI]

Ca

ORa

[95%CI]

Not exposed to any chlorinated solvent

1645

930

1

171

1

276

1

174

1

68

1

241

1

TCE

761

557

0.93

[0.77 to 1.13]

124

1.18

[0.87 to 1.59]

159

0.93

[0.71 to 1.21]

117

0.99

[0.73 to 1.35]

30

0.70

[0.42 to 1.14]

127

0.84

[0.63 to 1.12]

TCE, PCE

19

12

0.90

[0.36 to 2.23]

1

0.39

[0.05 to 3.19]

4

1.13

[0.33 to 3.50]

2

0.99

[0.20 to 4.94]

2

2.33

[0.46 to 11.67]

3

0.90

[0.24 to 3.16]

TCE, MC

122

131

0.91

[0.65 to 1.27]

21

0.81

[0.47 to 1.40]

39

0 .93

[0.59 to 1.46]

28

0.99

[0.60 to 1.65]

11

1.06

[0.51 to 2.20]

32

0.95

[0.59 to 1.53]

TCE, PCE, MC

62

49

1.05

[0.64 to 1.73]

9

1.00

[0.45 to 2.26]

13

0.91

[0.45 to 1.84]

10

1.11

[0.51 to 2.43]

1

0.26

[0.03 to 2.02]

16

1.32

[0.68 to 2.55]

  1. Abbreviations PCE perchloroethylene, TCE trichloroethylene, MC methylene chloride, CF chloroform, CT carbon tetrachloride, OR odds ratio, CI confidence interval, CEI cumulative cxposure index, Ca cases, Co controls
  2. aOR adjusted for age at interview, residence area, alcohol consumption, smoking status, frequency and duration of smoking, exposure to asbestos