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Table 3 Percentage change in scores on the K-SCQ associated with 2-fold increases in creatinine-adjusted prenatal and postnatal BPA levels

From: Prenatal and postnatal bisphenol A exposure and social impairment in 4-year-old children

Subcategory of K-SCQ score

Gender

Prenatal BPA

Postnatal BPA

% change (95% CI)

P-value

P-value for gender difference

% change (95% CI)

P-value

P-value for gender difference

Total

All

3.4 (−0.8, 7.7)

0.1134

0.2464

−1.0 (−5.1, 3.3)

0.6517

0.0034

Boys

3.7 (−1.4, 9.1)

0.1593

−5.2 (−10.3, 0.1)#

0.0553

Girls

2.2 (−4.6, 9.4)

0.5359

4.5 (−2.3, 11.8)

0.1966

Social interaction

All

−0.3 (−8.1, 8.1)

0.9365

0.3835

−5.6 (−13.1, 2.5)

0.1708

0.8667

Boys

−3.2 (−12.1, 6.7)

0.5129

−6.8 (−16.4, 3.8)

0.2003

Girls

7.0 (−7.0, 23.2)

0.3434

−5.7 (−17.4, 7.8)

0.3904

Social communication

All

3.5 (−3.1, 10.6)

0.3090

0.2167

2.0 (−4.9, 9.3)

0.5848

0.0054

Boys

6.4 (−2.3, 15.8)

0.1548

−5.2 (−13.5, 3.9)

0.2551

Girls

−1.0 (−10.8, 9.9)

0.8526

11.8 (0.6, 24.3)*

0.0392

Behavior patterns

All

5.5 (−1.9, 13.5)

0.1463

0.2075

−0.2 (−7.5, 7.6)

0.9510

0.0374

Boys

6.0 (−3.1, 16.1)

0.2020

−4.8 (−13.4, 4.5)

0.2999

Girls

3.2 (−8.7, 16.7)

0.6146

5.2 (−6.7, 18.6)

0.4102

  1. Models were adjusted for gender (boy or girl), parity (1st vs. other), mother’s education (high school or lower vs. more than high school), birth weight (kg), and use of plastic dishes in the microwave oven (yes or no). In addition, prenatal and postnatal BPA levels were mutually controlled for in the model
  2. Abbreviations: K-SCQ Korean version of the Social Communication Questionnaire, BPA bisphenol A, CI confidence interval
  3. * P-value <0.05; # P-value <0.1