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Table 7 Association between mtDNA content and PM exposure

From: Transcriptome-wide analyses indicate mitochondrial responses to particulate air pollution exposure

Time window

Men (n = 67)

Women (n = 83)

FC (95% CI)

P-val

FC (95% CI)

P-val

Short-term PM10

0.80 (0.67, 0.96)

0.02

0.82 (0.69, 0.97)

0.02

Short-term PM2.5

0.82 (0.69, 0.98)

0.03

0.83 (0.7, 0.98)

0.04

Medium-term PM10

0.77 (0.57, 1.04)

0.09

0.74 (0.55, 0.99)

0.05

Medium-term PM2.5

0.75 (0.55, 1.03)

0.08

0.73 (0.53, 1.01)

0.06

Long-term PM10

0.95 (0.87, 1.04)

0.26

0.9 (0.83, 0.97)

0.007

Long-term PM2.5

0.88 (0.72, 1.08)

0.22

0.76 (0.64, 0.91)

0.004

  1. FC Fold changes for an increase in PM of 10 μg/m3 (short- and medium-term) and 2 μg/m3 (long-term). Adjusted for age, BMI, smoking status, educational level, and time of blood sampling, temperature and WBC count and percentage of neutrophils
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Environmental Health

ISSN: 1476-069X