Skip to main content

Advertisement

Table 1 Participant characteristics by high-sensitivity C-reactive protein (hs-CRP) and plasma homocysteine (tHcy) in women, Buffalo, NY

From: Blood lead, cadmium and mercury in relation to homocysteine and C-reactive protein in women of reproductive age: a panel study

  Population (n = 259) hs-CRP <0.56 mg/L hs-CRP ≥0.56 mg/L p-value tHcy <5.9 μmol/L tHcy ≥5.9 μmol/L p-value
Age, years 27.4 ± 8.2 25.4 ± 7.3 29.5 ± 8.6 <0.01 28.1 ± 8.4 26.9 ± 8.1 0.28
BMI, kg/m2 24.1 ± 3.9 22.5 ± 2.8 25.9 ± 4.1 <0.01 23.9 ± 3.7 24.3 ± 4.0 0.36
Cadmium, μg/La 0.29 (0.26, 0.31) 0.29 (0.26, 0.32) 0.28 (0.25, 0.32) 0.85 0.26 (0.23, 0.30) 0.30 (0.27, 0.34) 0.12
Lead, μg/dLa 0.91 (0.86, 0.96) 0.92 (0.85, 1.00) 0.90 (0.84, 0.98) 0.78 0.83 (0.77, 0.90) 0.97 (0.90, 1.05) <0.01
Mercury, μg/La 1.05 (0.93, 1.18) 1.03 (0.86, 1.22) 1.07 (0.90, 1.28) 0.72 1.14 (0.94, 1.37) 0.99 (0.84, 1.17) 0.28
Estradiol, pg/mLa, b 51.22 (48.60, 53.98) 50.2 (45.4, 55.5) 50.4 (44.4, 56.7) 0.95 52.6 (46.4, 59.6) 48.9 (44.3, 53.9) 0.35
FSH, mIU/mLa, b 6.59 (6.39, 6.79) 6.51 (6.16, 6.88) 6.50 (6.03, 7.00) 0.97 6.40 (5.92, 6.90) 6.58 (6.21, 6.96) 0.94
LH, ng/mLa, c 9.55 (8.87, 10.30) 9.35 (8.14, 10.74) 9.54 (8.14, 11.18) 0.85 9.39 (8.11, 10.88) 9.48 (8.18, 10.99) 0.93
Progesterone, ng/ml a, d 6.16 (5.60, 6.77) 5.18 (4.18, 6.43) 6.41 (5.33, 7.71) 0.14 6.27 (5.20, 7.56) 5.22 (4.20, 6.49) 0.20
Serum folate, ng/mla 19.89 (19.40, 20.38) 19.8 (18.9, 20.8) 20.0 (19.1, 21.0) 0.70 21.3 (20.2, 22.4) 19.1 (18.3, 19.9) <0.01
Dietary folate, μg /daya 318.55 (303.0, 334.9) 331.4 (300.5, 365.5) 311.7 (281.0, 345.8) 0.40 349.2 (311.8, 391.2) 305.4 (278.9, 334.4) <0.01
Dietary Vitamin B6, mg/daya 1.25 (1.19, 1.32) 1.32 (1.19, 1.45) 1.26 (1.13, 1.42) 0.60 1.38 (1.23, 1.54) 1.24 (1.12, 1.37) 0.17
Dietary Vitamin B12, μg /daya 2.53 (2.33, 2.76) 2.67 (2.24, 3.18) 2.64 (2.24, 3.10) 0.92 3.06 (2.16, 3.58) 2.42 (2.05, 2.86) 0.04
Alcohol, litre/daya 0.14 (010, 0.21) 0.13 (0.06, 0.27) 0.20 (0.09, 0.47) 0.43 0.14 (0.05, 0.38) 0.17 (0.09, 0.33) 0.76
Total calories, Kcal/daya 1482.8 (1433, 1534) 1454 (1355, 1560) 1487 (1378, 1605) 0.67 1562 (1432, 1702) 1415 (1328, 1508) 0.06
Racee        
 White 148 (57) 71 (55) 77 (64) 0.18 56 (56) 92 (61) 0.24
 Black 51 (20) 26 (20) 25 (21) 26 (26) 25 (17)
 Asian 35 (14) 24 (19) 11 (9) 11 (11) 24 (16)
 Other 25 (10) 8 (6) 7 (6) 7 (7) 8 (5)
Smokinge        
 No/former 249 (96) 125 (97) 114 (95) 0.53 98 (98) 141 (54) 0.30
 Current 10 (4) 4 (3) 6 (5) 2 (2) 8 (5)
Paritye        
 0 187 (74) 109 (83) 78 (64) <0.01 66 (65) 121 (80) <0.01
  ≥ 1 66 (26) 22 (17) 44 (36) 36 (35) 30 (20)
  1. aGeometric mean (95% confidence limits) b Day 7 c Day 14 d Day 22
  2. eCategorical variables [race, smoking, parity] expressed as n (%)
  3. tHcy and hs-CRP concentrations dichotomized on cycle 1 day 7
  4. Continuous variables compared using t-test; categorical variables compared using Chi-square test or Fisher’s exact test