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Table 4 Age adjusted relative risk for all cancers, prostate cancer and malignant melanoma, by employment years, cumulative air hours, cumulative mSv, and cumulative mSv up to age of 40 years

From: Incidence of cancer among licenced commercial pilots flying North Atlantic routes

  All primary cancers (C00-C97) Prostate cancer (C61) Malignant melanoma (C43)
Exposure No Yes   No Yes   No Yes  
metrics n = 474 n = 77 RR (95% CI) n = 524 n = 27 RR (95% CI) n = 544 n = 7 RR (95% CI)
Employment years
 Unexposed 232 33 1.00 (Referent) 253 12 1.00 (Referent) 264 1 1.00 (Referent)
 <15 127 5 1.73 (0.51 to 5.18) 132 0 131 1 9.33 (0.22 to 596.01)
 15+ 115 39 2.34 (1.45 to 3.80) 139 15 2.40 (1.10 to 5.23) 149 5 9.55 (1.49 to 187.47)
 p-trend   0.002   0.05   0.02
Cumulative air hours
 Unexposed 232 33 1.00 (Referent) 253 12 1.00 (Referent) 264 1 1.00 (Referent)
 <10,000 163 7 1.40 (0.49 to 3.73) 170 0 169 1 3.27 (0.09 to 160.46)
 10,000+ 79 37 2.41 (1.50 to 3.90) 101 15 2.61 (1.22 to 5.60) 111 5 10.29 (1.66 to 197.12)
 p-trend   0.0001   0.01   0.004
Cumulative mSv
 Unexposed 232 33 1.00 (Referent) 253 12 1.00 (Referent) 264 1 1.00 (Referent)
 <25 145 6 1.36 (0.46 to 3.56) 151 0 150 1 5.07 (0.14 to 201.23)
 25+ 97 38 2.42 (1.50 to 3.92) 120 15 2.57 (1.18 to 5.56) 130 5 9.88 (1.57 to 190.78)
 p-trend   0.0005   0.02   0.009
Cumulative mSv up to age of 40 years
 Unexposed 232 33 1.00 (Referent) 253 12 1.00 (Referent) 264 1 1.00 (Referent)
 <5 120 5 1.53 (0.47 to 4.20) 125 0 125 0
 5+ 122 39 2.37 (1.47 to 3.85) 146 15 2.47 (1.13 to 5.41) 155 6 10.34 (1.23 to 86.61)
 p-trend   0.003   0.06   0.005
  1. Abbreviations: MilliSievert (mSv), relative risk (RR), confidence interval (CI)