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Table 4 Age adjusted relative risk for all cancers, prostate cancer and malignant melanoma, by employment years, cumulative air hours, cumulative mSv, and cumulative mSv up to age of 40 years

From: Incidence of cancer among licenced commercial pilots flying North Atlantic routes

 

All primary cancers (C00-C97)

Prostate cancer (C61)

Malignant melanoma (C43)

Exposure

No

Yes

 

No

Yes

 

No

Yes

 

metrics

n = 474

n = 77

RR (95% CI)

n = 524

n = 27

RR (95% CI)

n = 544

n = 7

RR (95% CI)

Employment years

 Unexposed

232

33

1.00 (Referent)

253

12

1.00 (Referent)

264

1

1.00 (Referent)

 <15

127

5

1.73 (0.51 to 5.18)

132

0

131

1

9.33 (0.22 to 596.01)

 15+

115

39

2.34 (1.45 to 3.80)

139

15

2.40 (1.10 to 5.23)

149

5

9.55 (1.49 to 187.47)

 p-trend

 

0.002

 

0.05

 

0.02

Cumulative air hours

 Unexposed

232

33

1.00 (Referent)

253

12

1.00 (Referent)

264

1

1.00 (Referent)

 <10,000

163

7

1.40 (0.49 to 3.73)

170

0

169

1

3.27 (0.09 to 160.46)

 10,000+

79

37

2.41 (1.50 to 3.90)

101

15

2.61 (1.22 to 5.60)

111

5

10.29 (1.66 to 197.12)

 p-trend

 

0.0001

 

0.01

 

0.004

Cumulative mSv

 Unexposed

232

33

1.00 (Referent)

253

12

1.00 (Referent)

264

1

1.00 (Referent)

 <25

145

6

1.36 (0.46 to 3.56)

151

0

150

1

5.07 (0.14 to 201.23)

 25+

97

38

2.42 (1.50 to 3.92)

120

15

2.57 (1.18 to 5.56)

130

5

9.88 (1.57 to 190.78)

 p-trend

 

0.0005

 

0.02

 

0.009

Cumulative mSv up to age of 40 years

 Unexposed

232

33

1.00 (Referent)

253

12

1.00 (Referent)

264

1

1.00 (Referent)

 <5

120

5

1.53 (0.47 to 4.20)

125

0

125

0

 5+

122

39

2.37 (1.47 to 3.85)

146

15

2.47 (1.13 to 5.41)

155

6

10.34 (1.23 to 86.61)

 p-trend

 

0.003

 

0.06

 

0.005

  1. Abbreviations: MilliSievert (mSv), relative risk (RR), confidence interval (CI)