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Table 1 Types of studies based on which the level of convincing evidence of carcinogenicity was reached for a number of exposuresa

From: The hazards of hazard identification in environmental epidemiology

Exposure

Type of study

Tobacco smoke

Cohort studies

Diethylstilbestrol

Case-control study (small)

Bis(chloromethyl)ether

Case series

Benzene

Case reports

Arsenic

Ecological study

Several chemotherapeutic drugs

Controlled randomized trials

  1. aSource: [16]. Evidence rated as convincing when corresponding exactly or closely to category 1 or 2A in the current definitions of IARC [3]