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Table 5 Odds ratio (OR) of amyotrophic lateral sclerosis for current proximity to agricultural fields in tertiles of current exposurea

From: Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis

  Total Emilia-Romagna Sicily
  I II III I II III I II III
Total agricultural land
 Cut off (%) <12.2 12.2-38.8 >38.8 <17.2 17.2-44.6 >44.6 <6.3 6.3-21.6 >21.6
 Cases/Controls 487/1949 113/394 103/394 354/1363 80/286 65/286 138/586 25/108 41/108
 OR (95% CI) 1.00 1.15 (0.91, 1.45) 1.04 (0.82, 1.33) 1.00 1.08 (0.82, 1.43) 0.88 (0.65, 1.18) 1.00 0.97 (0.60, 1.57) 1.57 (1.06, 2.34)
Vineyards
 Cut off (%) <9.7 9.7-31.1 >31.1 <9.8 9.8-31.5 >31.5 <2.8 2.8-9.4 >9.4
 Cases/Controls 683/2677 11/30 9/30 480/1877 11/29 8/29 203/800 0/1 1/1
 OR (95% CI) 1.00 1.46 (0.72, 2.95) 1.19 (0.55, 2.54) 1.00 1.51 (0.74, 3.07) 1.10 (0.49, 2.44) 1.00 -   3.47 (0.22, 55.83)
Orchards
 Cut off (%) <7.8 7.8-26.4 >26.4 <9.6 9.6-28.9 >28.9 <7.5 7.5-23.4 >23.4
 Cases/Controls 675/2618 15/59 13/60 497/1871 1/33 1/31 179/746 12/29 13/27
 OR (95% CI) 1.00 0.98 (0.55, 1.74) 0.85 (0.46, 1.57) 1.00 0.11 (0.02, 0.82) 0.11 (0.02, 0.84) 1.00 1.74 (0.86, 3.49) 1.94 (1.00, 3.77)
Arable crops
 Cut off (%) <13.1 13.1-38.7 >38.7 <14.9 14.9-40.9 >40.9 <3.9 3.9-17.1 >17.1
 Cases/Controls 551/2187 89/275 63/275 359/1431 82/252 58/252 196/756 2/23 6/23
 OR (95% CI) 1.00 1.29 (0.99, 1.69) 0.91 (0.68, 1.22) 1.00 1.31 (0.99, 1.73) 0.91 (0.67, 1.24) 1.00 0.35 (0.08, 1.48) 1.01 (0.40, 2.54)
Vegetable crops
 Cut off (%) <6.4 6.4-20.9 >20.9 <8.1 8.1-20.9 >20.9 <4.8 - >4.8
 Cases/Controls 701/2734 1/2 1/1 498/1933 0/1 1/1 203/801 0/0 1/1
 OR (95% CI) 1.00 1.81 (0.16, 20.08) 4.00 (0.25, 63.95) 1.00 -   4.00 (0.25, 63.95) 1.00 -   3.46 (0.22, 55.78)
Olive groves
 Cut off (%)            <2.9 2.9-9.1 >9.1
 Cases/Controls            199/795 0/4 5/3
 OR (95% CI)            1.00 -   6.44 (1.54, 26.98)
  1. aTertile cutpoints based on exposure of subjects having proximity to crops >0, with subjects having exposure = 0 included in the bottom tertile. OR computed using a conditional logistic regression model. Some estimates could not be computed because of too few exposed subjects