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Table 6 Odds ratios (OR) of amyotrophic lateral sclerosis associated with historical proximity to any agricultural land or specific crop type within 100 m from residence (A), and with 20% increase of crop type (B)a

From: Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis

  Cases Controls Total (N = 2235) Cases Controls Emilia-Romagna (N = 1363) Cases Controls Sicily (N = 872)
Crops Exp/Unexp Exp/Unexp OR (95% CI) Exp/Unexp Exp/Unexp OR (95% CI) Exp/Unexp Exp/Unexp OR (95% CI)
(A)
 Total agricultural land 258/271 772/934 1.05 (0.83, 1.32) 224/119 661/359 1.02 (0.77, 1.33) 34/152 111/575 1.15 (0.75, 1.77)
 Vineyards 28/501 122/1584 0.64 (0.41, 0.99) 28/315 121/899 0.64 (0.41, 0.99) 0/186 1/685 -  
 All Orchards 40/489 124/1582 1.06 (0.72, 1.55) 16/327 55/965 0.82 (0.46, 1.47) 24/162 69/617 1.31 (0.79, 2.18)
 Orchards (not citrus) 16/513 59/1647 0.77 (0.43, 1.38) 16/327 55/965 0.82 (0.46, 1.47) 0/186 4/682 -  
 Citrus orchards          24/162 65/621 1.40 (0.84, 2.32)
 Arable and Veg. crops 213/316 627/1079 1.04 (0.80, 1.35) 213/130 613/407 1.11 (0.85, 1.44) 0/186 14/672 -  
 Arable crops      211/132 611/409 1.08 (0.83, 1.41)     
 Vegetables crops      2/341 3/1017 2.67 (0.45, 15.96)     
 Olive groves          3/183 5/681 2.23 (0.53, 9.35)
(B)
 Total agricultural land    1.05 (0.98, 1.12)    1.02 (0.94, 1.10)    1.18 (1.02, 1.36)
 Vineyards    0.85 (0.60, 1.20)    0.86 (0.60, 1.23)    -  
 All Orchards    1.13 (0.96, 1.34)    0.91 (0.60, 1.37)    1.20 (1.00, 1.44)
 Orchards (not citrus)        0.91 (0.60, 1.37)    -  
 Citrus orchards            1.23 (1.02, 1.48)
 Arable and Veg. crops    1.03 (0.95, 1.12)    1.04 (0.95, 1.13)    -  
 Arable crops        1.03 (0.94, 1.12)     
 Vegetables crops        -      
 Olive groves            Too high
  1. aResults for dichotomous analysis expressed as crude OR for matched sets, and for continuous analysis using a conditional logistic regression model. Some estimates could not be computed because of too few exposed subjects