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Table 6 Odds ratios (OR) of amyotrophic lateral sclerosis associated with historical proximity to any agricultural land or specific crop type within 100 m from residence (A), and with 20% increase of crop type (B)a

From: Pesticide exposure assessed through agricultural crop proximity and risk of amyotrophic lateral sclerosis

 

Cases

Controls

Total (N = 2235)

Cases

Controls

Emilia-Romagna (N = 1363)

Cases

Controls

Sicily (N = 872)

Crops

Exp/Unexp

Exp/Unexp

OR

(95% CI)

Exp/Unexp

Exp/Unexp

OR

(95% CI)

Exp/Unexp

Exp/Unexp

OR

(95% CI)

(A)

 Total agricultural land

258/271

772/934

1.05

(0.83, 1.32)

224/119

661/359

1.02

(0.77, 1.33)

34/152

111/575

1.15

(0.75, 1.77)

 Vineyards

28/501

122/1584

0.64

(0.41, 0.99)

28/315

121/899

0.64

(0.41, 0.99)

0/186

1/685

-

 

 All Orchards

40/489

124/1582

1.06

(0.72, 1.55)

16/327

55/965

0.82

(0.46, 1.47)

24/162

69/617

1.31

(0.79, 2.18)

 Orchards (not citrus)

16/513

59/1647

0.77

(0.43, 1.38)

16/327

55/965

0.82

(0.46, 1.47)

0/186

4/682

-

 

 Citrus orchards

        

24/162

65/621

1.40

(0.84, 2.32)

 Arable and Veg. crops

213/316

627/1079

1.04

(0.80, 1.35)

213/130

613/407

1.11

(0.85, 1.44)

0/186

14/672

-

 

 Arable crops

    

211/132

611/409

1.08

(0.83, 1.41)

    

 Vegetables crops

    

2/341

3/1017

2.67

(0.45, 15.96)

    

 Olive groves

        

3/183

5/681

2.23

(0.53, 9.35)

(B)

 Total agricultural land

  

1.05

(0.98, 1.12)

  

1.02

(0.94, 1.10)

  

1.18

(1.02, 1.36)

 Vineyards

  

0.85

(0.60, 1.20)

  

0.86

(0.60, 1.23)

  

-

 

 All Orchards

  

1.13

(0.96, 1.34)

  

0.91

(0.60, 1.37)

  

1.20

(1.00, 1.44)

 Orchards (not citrus)

      

0.91

(0.60, 1.37)

  

-

 

 Citrus orchards

          

1.23

(1.02, 1.48)

 Arable and Veg. crops

  

1.03

(0.95, 1.12)

  

1.04

(0.95, 1.13)

  

-

 

 Arable crops

      

1.03

(0.94, 1.12)

    

 Vegetables crops

      

-

     

 Olive groves

          

Too high

  1. aResults for dichotomous analysis expressed as crude OR for matched sets, and for continuous analysis using a conditional logistic regression model. Some estimates could not be computed because of too few exposed subjects