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Table 1 Select characteristics of AHS farm spouses at enrollment with OC insecticide personal use information (n = 28,909)a

From: A prospective study of cancer risk among Agricultural Health Study farm spouses associated with personal use of organochlorine insecticides

  Any OC useb  
Never Ever  
N = 26,718 % N = 2,191 % p value±
Age at enrollment
 ≤ 44 13,153 49.23 447 20.40 < .0001
 45–54 6,677 24.99 771 35.19  
 55–64 4,823 18.05 731 33.36  
 ≥ 65 2,065 7.73 242 11.05  
Race
 White 26,164 97.93 2,178 99.4 < .0001
 Other 510 1.91 8 0.37  
 Missing 44 0.16 5 0.23  
State of Residence
 North Carolina 8,739 32.71 632 28.85 0.0002
 Iowa 17,979 67.29 1,559 71.15  
Educational Attainment
 High School or less 13,905 52.04 1,102 50.3 0.0015
 Some College or College Graduate 8,662 32.42 679 30.99  
 1 or more years of Graduate School 3,833 14.35 378 17.25  
 Missing 318 1.19 32 1.46  
Body Mass Index
 0–24.99 11,756 40.67 902 41.17 < .0001
 25.00–29.99 7,448 25.76 717 32.72  
 ≥ 30.00 4,298 14.87 440 20.08  
 Missing 3,216 11.12 132 6.02  
Alcohol
 Never 12,042 45.07 939 42.86 0.2371
 Less than once/month 7,099 26.57 603 27.52  
 ≥ 1–3 times per month 7,277 27.24 621 28.34  
 Missing 300 1.12 28 1.28  
Cigarette Smoking (Pack-years)
 Never Smoker 18,820 70.44 1,493 68.14 0.0003
 ≤ 6.75 3,544 13.26 294 13.42  
 6.751–16.75 1,752 6.56 127 5.80  
 ≥ 16.751 1,700 6.36 186 8.49  
 Missing 902 3.38 91 4.15  
Family History of Cancer
 No/Missing 13,949 52.21 949 43.31 < .0001
 Yes 12,769 47.79 1,242 56.69  
Grew up on a farm
 No 10,913 40.85 534 24.37 < .0001
 Yes 15,579 58.30 1,643 74.99  
 Missingc 226 0.85 14 0.64  
Menopause at Enrollment
 No 8,922 33.39 534 24.37 < .0001
 Yes 6,777 25.36 1,127 51.44  
 Unsure 245 0.92 22 1.00  
 Missingc 10,774 40.32 508 23.19  
Number of Live Births
 0 235 0.88 29 1.32 < .0001
 1 or 2 7,216 27.01 688 31.40  
 > 2 7,526 28.17 887 40.48  
 Missingc 11,741 43.94 587 26.79  
Oral Contraceptive Use
 Never 4,236 15.85 576 26.29 < .0001
 Ever 11,722 43.87 1,106 50.48  
 Missingc 10,760 40.27 509 23.23  
Age of first menarche
 12 years or less 7,099 26.57 788 35.97 < .0001
 13 years 4,851 18.16 493 22.5  
 14 years or greater 3,855 14.43 398 18.17  
 Missingc 10,913 40.85 512 23.37  
OC Insecticides
 Overall OC (Any OC) - - 2,191 7.58 -
 Chlordane - - 1,196 4.13 -
 DDT - - 1,028 3.55 -
 Lindane - - 430 1.47 -
 Aldrin - - 235 0.81 -
 Hepatchlor - - 222 0.77 -
 Toxaphene - - 203 0.70 -
 Dieldrin - - 105 0.36 -
  1. AHS Agricultural Health Study, RR relative risks, OC organochlorines
  2. ±Chi Square test for homogeneity
  3. aExcluded: n = 2146 with missing information for personal use of all OCs; n = 905 female spouses diagnosed with cancer prior to enrollment; n = 219 male spouses; n = 161 with missing or 0 person-years of follow-up leaving a total n = 28,909 female farm spouses
  4. bEver use of any of the seven OC insecticides
  5. cFrom Female & Family Health Questionnaire responses