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Table 3 Association of blood lead level with non-alcohol fatty liver disease

From: Blood lead level is associated with non-alcoholic fatty liver disease in the Yangtze River Delta region of China in the context of rapid urbanization

 

Blood lead level quartiles

 

Variables

Q1

Q2

Q3

Q4

P for trend

Men

 Blood lead level, μg/dL

≤3.60

3.61–5.29

5.30–7.28

≥7.29

 

NAFLD

 Model 1

Ref.

1.107 (0.670–1.829)

1.366 (0.832–2.244)

1.644 (1.003–2.695)*

0.033

 Model 2

Ref.

1.261 (0.695–2.287)

1.394 (0.770–2.523)

1.858 (1.007–3.429)*

0.048

 Model 3

Ref.

1.695 (0.841–3.419)

1.837 (0.875–3.858)

2.168 (0.989–4.750)

0.063

Women

 Blood lead level, μg/dL

≤2.97

2.98–4.49

4.50–6.59

≥6.60

 

NAFLD

 Model 1

Ref.

1.238 (0.918–1.669)

1.424 (1.058–1.917)*

1.818 (1.353–2.443)***

<0.001

 Model 2

Ref.

1.276 (0.915–1.779)

1.585 (1.140–2.204)**

1.686 (1.211–2.348)**

0.001

 Model 3

Ref.

1.384 (0.956–2.005)

1.495 (1.024–2.181) *

1.613 (1.082–2.405)*

0.019

  1. Data were odds ratio (95% confidence interval). * P < 0.05; ** P < 0.01; *** P < 0.001
  2. Model 1 was unadjusted
  3. Model 2 was adjusted for age, geography (Shanghai/Zhejiang), educational level, current smoking, current drinking and alanine transaminase
  4. Model 3 was additionally adjusted for diabetes, waist circumference, body mass index, low-density lipoprotein, high-density lipoprotein, triglycerides, total cholesterol and blood cadmium level