Table 5 Summary of exploratory analyses considering synergism of exposure to PBDEs and OC pesticides on all-cause and other-cause mortality
From: Persistent organic pollutants and mortality in the United States, NHANES 1999–2011
HR (95%CI)a, all-cause mortality Σ PBDEs above LOD in >90% | HR (95%CI)a, other-cause mortality Σ PBDEs above LOD in >90% | ||||||
|---|---|---|---|---|---|---|---|
Less than median | Higher than median | interaction p-value | Less than median | Higher than median | interaction p-value | ||
Trans-nonachlor | Less than median | 1.0 (Ref.) | 1.08 (0.58, 2.00) | 0.09 | 1.0 (Ref.) | 0.47 (0.12, 1.86) | 0.24 |
Higher than median | 1.07 (0.67, 1.70) | 1.96 (1.11, 3.43) | 0.95 (0.47, 1.94) | 1.00 (0.52, 1.93) | |||
p,p’-DDE | Less than median | 1.0 (Ref.) | 1.10 (0.63, 1.94) | 0.08 | 1.0 (Ref.) | 0.37 (0.17, 0.81) | 0.01 |
Higher than median | 0.84 (0.46, 1.54) | 1.63 (1.03, 2.59) | 0.93 (0.42, 2.08) | 1.06 (0.46, 2.42) | |||
Oxychlordane | Less than median | 1.0 (Ref.) | 0.90 (0.40, 2.04) | 0.14 | 1.0 (Ref.) | 0.88 (0.39, 1.97) | 0.29 |
Higher than median | 0.87 (0.50, 1.51) | 1.60 (1.00, 2.54) | 0.34 (0.05, 2.49) | 0.96 (0.54, 1.70) | |||
β-hexachlorocyclohexane | Less than median | 1.0 (Ref.) | 1.13 (0.61, 2.10) | 0.26 | 1.0 (Ref.) | 0.60 (0.17, 2.1) | 0.49 |
Higher than median | 0.78 (0.41, 1.48) | 1.43 (0.86, 2.74) | 0.78 (0.36, 1.70) | 0.76 (0.37, 1.54) | |||