Skip to main content

Table 1 Sample characteristics in terms of exposure, biochemistry and outcome (N = 178)

From: Polychlorinated biphenyls and depression: cross-sectional and longitudinal investigation of a dopamine-related Neurochemical path in the German HELPcB surveillance program

 

reference value

t1

t2

 

Mean ± SD

Median

Range

Mean ± SD

Median

Range

LPCBsa

3.9a,c

402.8 ± 1887.5

21.2

1.3–19,345.0

303.4 ± 1493.2

12.8

1.4–14,090.4

HPCBsa

264.8a,c

964.9 ± 1780.3

331.0

40.5–13,855.3

901.2 ± 1646.7

302.1

43.1–11,794.2

dlPCBsa

30.7a,c

345.4 ± 775.3

62.2

7.0–6051.8

313.7 ± 756.6

53.6

8.3–6342.9

HVA/creab

<42b;d

19.8 ± 9.2

18.1

6.3–79.0

22.3 ± 12.8

19.2

10.0–115.1

VMA/creab

<30b;d

15.4 ± 5.7

14.6

7.0–46.0

15.8 ± 6.2

15.3

2.2–48.8

depressive symptoms

18e

6.3 ± 6.4

5.0

0–38

6.6 ± 7.0

5.0

0–40

  1. Note: LPCBs lower-chlorinated biphenyls (28, 52, 101), HPCBs higher-chlorinated biphenyls (138, 153, 180), dlPCBs dioxin-like polychlorinated biphenyls (105, 114, 118, 123, 156, 157, 167, 189), HVA homovanillic acid, VMA vanillylmandelic acid, crea creatinine, SD standard deviation, t1 measurement occasion 1, t2 measurement occasion 2
  2. ain ng/g lipid
  3. bin μmol/g Crea
  4. cmedian of PCB exposure in the German general population; data source Schettgen et al. [23]
  5. dintern laboratory reference value
  6. ecut of value for clinically relevant depression [50]