In-utero exposure to phenols and phthalates and the intelligence quotient of boys at 5 years

Table 2 Concentrations^a of phenols and phthalate metabolites in maternal urine (N = 452^b mother-son pairs of the EDEN mother child cohort)

Compounds (μg/L)	LOD (μg/L)	% < LOD	Percentiles
Compounds (μg/L)	LOD (μg/L)	% < LOD	5th	50th	95th
Phenols
2,4-dichlorophenol	0.2	2	0.3	1.0	10.0
2,5-dichlorophenol	0.2	0	1.7	9.2	305
Bisphenol A	0.4	0.4	0.9	2.4	9.3
Benzophenone-3	0.4	7	<LOD	2.2	63.7
Triclosan	2.3	18	<LOD	25.6	691
Methyl paraben	1	0	8.0	101	1529
Ethyl paraben	1	27	<LOD	3.4	689
Propyl paraben	0.2	1	0.5	13.4	255
Butyl paraben	0.2	14	<LOD	2	57.7
Phthalates
Monoethyl phthalate (MEP)	0.6	0	21.9	100	591
Mono-n-butyl phthalate (MBP)	0.2	0	11.6	44.6	444
Mono-isobutyl phthalate (MiBP)	0.2	0	11.8	38.8	168
Mono(2-ethyl-5-carboxypentyl) phthalate (MECPP)	0.2	0	12.5	39.2	176
Mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP)	0.2	0	6.9	29.0	106
Mono(2-ethyl-5-oxohexyl) phthalate (MEOHP)	0.2	0	5.8	23.3	87
Mono(2-ethylhexyl) phthalate (MEHP)	0.5	3	1.5	7.6	37
Monobenzyl phthalate (MBzP)	0.3	0	4.7	18.9	114
Monocarboxy-isooctyl phthalate (MCOP)	0.2	0	1.1	4.0	19
Mono(3-carboxypropyl) phthalate (MCPP)	0.2	0	0.8	2.0	9.4
Monocarboxy-isononyl phthalate (MCNP)	0.2	1	0.4	1.3	9.7
Creatinine			0.4	1.0	1.8

^aConcentrations were standardized for creatinine concentrations and sampling conditions including hour of sampling, gestational age at collection and duration of storage at room temperature before freezing, day of sampling, year of biomarkers assessment
^bRestricted to mother-son pairs with biomarker concentrations and IQ scores at 5–6 years available

ISSN: 1476-069X