Skip to main content

Table 5 Repeated measures analysis of combined age 5 and 8 years: Associations of lung function measurements in relation to weighted road density within a 50 m radius of home and stratified by fish oil supplementation restricted to non-movers between age 5 and 8 years

From: Childhood fish oil supplementation modifies associations between traffic related air pollution and allergic sensitisation

  No fish oil supplementation Fish oil supplementation p-value for interaction
N Mean Difference 95% CI p-value N Mean Difference 95% CI p-value  
log(FEV1 pre bronchodilator (L)) 114 −0.06 −0.11−0.02 0.009 101 0 − 0.04−0.04 0.938 0.088
log(FEV1 post bronchodilator (L)) 111 −0.04 −0.08−0.00 0.050 100 −0.01 − 0.05−0.02 0.505 0.508
log (FVC pre bronchodilator (L)) 113 −0.03 −0.07−0.01 0.200 99 0 −0.04−0.04 0.997 0.680
log (FVC post bronchodilator (L)) 110 −0.01 −0.05−0.03 0.587 98 0 −0.04−0.03 0.846 0.843
FEV1/FVC ratio pre bronchodilator 113 −0.03 −0.05--0.01 0.014 99 0 −0.02−0.02 0.979 0.031
FEV1/FVC ratio post bronchodilator 110 −0.02 −0.04−0.01 0.010 98 −0.01 −0.02−0.01 0.239 0.139
pre Peak Expiratory Flow (PEF) 91 4.33 −4.09−12.75 0.313 85 −0.55 −7.14−6.04 0.871 0.252
post Peak Expiratory Flow (PEF) 90 8.46 −0.07−16.98 0.051 84 −2.57 −9.29−4.14 0.453 0.056
Pre forced expiratory flow at 50% vital capacity (FEF50) 91 −0.09 −0.22−0.05 0.227 85 0.01 −0.11−0.13 0.893 0.380
Post forced expiratory flow at 50% vital capacity (FEF50) 90 −0.08 −0.23−0.08 0.333 84 −0.09 −0.22−0.04 0.19 0.757
Pre forced expiratory flow at mid-expiratory phase (FEF25–75) 91 −0.07 −0.18−0.05 0.270 85 −0.02 −0.12−0.08 0.743 0.747
Post forced expiratory flow at mid-expiratory phase (FEF25–75) 90 −0.03 −0.16−0.11 0.701 84 −0.08 −0.20−0.03 0.161 0.369
  1. All models are adjusted for age at spirometry, height at spirometry, weight at spirometry, sex, father’s education, mother’s education, environmental tobacco smoke exposure, breastfed to 6 months, any dog owned by 5 or 8 years, any cat owned by 5 or 8 years, maternal smoking in pregnancy, gas cooking at home
  2. Interaction term of fish oil supplementation with weighted road density was added as a separate term into a random intercept Poisson model. Mean difference, Relative Risks (RRs) and 95% confidence intervals (95% CI) represent increase in risk per unit increase in weighted road density, representing 100 m local road or 33.3 m of motorway within 50 m of the home. N = number of children