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Table 5 Repeated measures analysis of combined age 5 and 8 years: Associations of lung function measurements in relation to weighted road density within a 50 m radius of home and stratified by fish oil supplementation restricted to non-movers between age 5 and 8 years

From: Childhood fish oil supplementation modifies associations between traffic related air pollution and allergic sensitisation

 

No fish oil supplementation

Fish oil supplementation

p-value for interaction

N

Mean Difference

95% CI

p-value

N

Mean Difference

95% CI

p-value

 

log(FEV1 pre bronchodilator (L))

114

−0.06

−0.11−0.02

0.009

101

0

− 0.04−0.04

0.938

0.088

log(FEV1 post bronchodilator (L))

111

−0.04

−0.08−0.00

0.050

100

−0.01

− 0.05−0.02

0.505

0.508

log (FVC pre bronchodilator (L))

113

−0.03

−0.07−0.01

0.200

99

0

−0.04−0.04

0.997

0.680

log (FVC post bronchodilator (L))

110

−0.01

−0.05−0.03

0.587

98

0

−0.04−0.03

0.846

0.843

FEV1/FVC ratio pre bronchodilator

113

−0.03

−0.05--0.01

0.014

99

0

−0.02−0.02

0.979

0.031

FEV1/FVC ratio post bronchodilator

110

−0.02

−0.04−0.01

0.010

98

−0.01

−0.02−0.01

0.239

0.139

pre Peak Expiratory Flow (PEF)

91

4.33

−4.09−12.75

0.313

85

−0.55

−7.14−6.04

0.871

0.252

post Peak Expiratory Flow (PEF)

90

8.46

−0.07−16.98

0.051

84

−2.57

−9.29−4.14

0.453

0.056

Pre forced expiratory flow at 50% vital capacity (FEF50)

91

−0.09

−0.22−0.05

0.227

85

0.01

−0.11−0.13

0.893

0.380

Post forced expiratory flow at 50% vital capacity (FEF50)

90

−0.08

−0.23−0.08

0.333

84

−0.09

−0.22−0.04

0.19

0.757

Pre forced expiratory flow at mid-expiratory phase (FEF25–75)

91

−0.07

−0.18−0.05

0.270

85

−0.02

−0.12−0.08

0.743

0.747

Post forced expiratory flow at mid-expiratory phase (FEF25–75)

90

−0.03

−0.16−0.11

0.701

84

−0.08

−0.20−0.03

0.161

0.369

  1. All models are adjusted for age at spirometry, height at spirometry, weight at spirometry, sex, father’s education, mother’s education, environmental tobacco smoke exposure, breastfed to 6 months, any dog owned by 5 or 8 years, any cat owned by 5 or 8 years, maternal smoking in pregnancy, gas cooking at home
  2. Interaction term of fish oil supplementation with weighted road density was added as a separate term into a random intercept Poisson model. Mean difference, Relative Risks (RRs) and 95% confidence intervals (95% CI) represent increase in risk per unit increase in weighted road density, representing 100 m local road or 33.3 m of motorway within 50 m of the home. N = number of children