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Table 4 Menarche hazard ratio (95% CI) associated with log(ng/ml) increase in biomarker stratified by Tanner stagea

From: Childhood and adolescent phenol and phthalate exposure and the age of menarche in Latina girls

 

Tanner Stage

Biomarker

B1

B4

2,5-Dichlorophenol

1.13* (1.01, 1.27)

0.96 (0.85, 1.08)

Benzophenone-3

1.17** (1.06, 1.29)

0.99 (0.91, 1.06)

ΣDEHPb

0.77* (0.60, 0.98)

1.24 (0.97, 1.57)

MECPP

0.79 (0.61, 1.01)

1.24 (0.97, 1.58)

MEHHP

0.77* (0.62, 0.96)

1.22 (0.98, 1.51)

MEHP

0.80* (0.65, 0.98)

1.20 (0.98, 1.47)

MEOHP

0.78* (0.63, 0.97)

1.20 (0.96, 1.50)

MMP

0.96 (0.81, 1.14)

1.30** (1.10, 1.53)

  1. aAccelerated failure time model adjusting for BMI Z-score and maternal education; including an interaction between Tanner stage at biomarker measurement and concentration; restricted to subset of associations for which the interaction with the timing of biomarker measurement was significant (p < 0.05)
  2. bunits in log(nmol/l) reflecting the log transformed summation of DEHP metabolite concentrations
  3. *p < 0.05, **p < 0.01, ***p < 0.001