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Table 1 Characteristics of Ukrainian CLL cases

From: Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers

Variable

Exposed (UR-CLL)a

Unexposed (UN-CLL)b

Cases, N

16

28

Age at diagnosis, median (range), years

61 (49–78)

58 (41–76)

Sex

Male

Male

Diagnosis year, range

1986–2006

2002–2014

Blood count, median (range), 10 × 9 per mL

13 (2–55)

54 (16–122)

Rai stage, n (%)

 

NaNc

 0

1 (6)

 

 1

3 (19)

 

 2

9 (56)

 

 3

3 (19)

 

Smoking history, n (%)

 

NaNc

 never or former

9 (56)

 

 less than 20 cigarettes/day

5 (31)

 

 20 or more cigarettes/day

2 (13)

 

Alcohol consumption

 

NaNc

 never

4 (25)

 

 no more than 2–3 times a month

7 (44)

 

 once a week or more

5 (31)

 

Bone marrow radiation dose, median (range), milligray (mGy)

40.56 (0.24–1536.24)

NAd

POT1 mutation, n (%)

4 (25)

0 (0)

Telomere length, median (range), kilobytes (kb)

1.58 (0.12–9.06)

0.30 (0.09–2.47)

Survival after diagnosis, median (range), years

4 (1–18)

NaNc

  1. Based on 15 cases who have died by the end of follow-up
  2. aCLL cases in Chornobyl cleanup workers from Ukraine exposed to ionizing gamma-ray radiation
  3. bSex- and age-matched CLL cases from the general population of Ukraine unexposed to ionizing radiation
  4. cNaN = Not Available
  5. dNA = Not Applicable