Characteristic | Entire cohort (n = 7,665) | Silica exposure levela | |||
---|---|---|---|---|---|
Unexposed (n = 4,007) | Low (n = 1,218) | Medium (n = 1,220) | High (n = 1,220) | ||
Male gender (n, %) | 6542 (85.35) | 3023 (75.44) | 1160 (95.24) | 1181 (96.80) | 1178 (96.56) |
Year at birth | 1939.50 ± 9.60 | 1940.23 ± 9.48 | 1943.15 ± 9.08 | 1938.77 ± 9.40 | 1934.15 ± 8.29 |
Year at hire | 1962.28 ± 7.06 | 1963.01 ± 6.83 | 1965.87 ± 6.17 | 1962.06 ± 6.19 | 1956.51 ± 5.94 |
Age at hire (years) | 22.78 ± 5.76 | 22.78 ± 5.89 | 22.72 ± 5.57 | 23.29 ± 5.92 | 22.36 ± 5.30 |
Ever smoker (n, %)b | 5070 (66.14) | 2338 (58.35) | 893 (73.32) | 926 (75.90) | 913 (74.84) |
Never smoker (n, %)b | 2595 (33.86) | 1669 (41.65) | 325 (26.68) | 294 (24.10) | 307 (25.16) |
Pack-years of ever smoker b | 28.57 ± 15.39 | 28.27 ± 14.95 | 26.52 ± 14.11 | 29.03 ± 16.74 | 30.86 ± 15.95 |
Age at first exposure (years)c | 23.65 ± 6.36 | NA | 24.54 ± 7.27 | 23.79 ± 6.09 | 22.63 ± 5.44 |
Cumulative total dust concentration (mg/m3-y)c | 117.95 ± 70.27 | NA | 55.21 ± 21.94 | 107.32 ± 18.41 | 191.22 ± 67.66 |
Average total dust concentration (mg/m3)c | 5.29 ± 3.02 | NA | 3.88 ± 2.49 | 4.66 ± 2.05 | 7.34 ± 3.22 |
Cumulative respirable dust concentration (mg/m3-y)c | 18.48 ± 11.01 | NA | 10.34 ± 6.53 | 18.02 ± 7.03 | 27.08 ± 11.46 |
Average respirable dust concentration (mg/m3)c | 0.83 ± 0.47 | NA | 0.69 ± 0.47 | 0.77 ± 0.37 | 1.03 ± 0.50 |
Cumulative respirable silica dust concentration (mg/m3-y)c | 0.83 ± 0.80 | NA | 0.34 ± 0.13 | 0.66 ± 0.10 | 1.51 ± 1.07 |
Average respirable silica dust concentration (mg/m3)c | 0.04 ± 0.04 | NA | 0.02 ± 0.02 | 0.03 ± 0.01 | 0.06 ± 0.06 |
Duration of dust exposure (years)c | 23.95 ± 9.29 | NA | 18.12 ± 9.65 | 25.55 ± 7.13 | 28.17 ± 7.80 |
Pneumoconiosis cases (n, %)d | 332 (9.08) | NA | 21 (1.72) | 79 (6.48) | 232 (19.02) |
Age of first diagnosis of pneumoconiosis (years)d | 49.64 ± 8.83 | NA | 51.11 ± 12.88 | 50.84 ± 9.04 | 49.11 ± 8.29 |
Latency of pneumoconiosis (years)d | 25.60 ± 8.00 | NA | 23.67 ± 9.32 | 24.69 ± 7.69 | 26.08 ± 7.96 |
Age upon entry to cohort (years) | 24.84 ± 6.73 | 24.39 ± 6.61 | 23.63 ± 6.18 | 25.05 ± 6.67 | 27.34 ± 7.09 |
Median of follow-up (years)e | 42.75 ± 12.00 | 42.34 ± 14.00 | 41.92 ± 5.92 | 43.09 ± 10.04 | 45.34 ± 14.33 |
Deceased (n, %) | 2814 (36.71) | 1233 (30.77) | 401 (32.92) | 515 (42.21) | 665 (54.51) |