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Table 1 Single-pollutant associations between average phthalate exposures and gestational age

From: Associations between mixtures of urinary phthalate metabolites with gestational age at delivery: a time to event analysis using summative phthalate risk scores

Phthalate Metabolite

Logistic*

Cox

AFT

OR

95% CI

HR

95% CI

% Change

95% CI

MEHP

1.50

(1.10, 2.07)

1.07

(0.98, 1.17)

−0.79%

(−1.67, 0.09%)

MEHHP

1.05

(0.75, 1.47)

1.04

(0.94, 1.15)

−0.51%

(−1.01, 0.32%)

MEOHP

1.23

(0.87, 1.75)

1.09

(0.98, 1.21)

−0.76%

(−1.74, 0.23%)

MECPP

1.66

(1.20, 2.30)

1.21

(1.09, 1.33)

−1.19%

(−2.11, −0.26%)

Σ DEHP

1.47

(1.06, 2.03)

1.14

(1.04, 1.26)

−1.03%

(−1.95, −0.01%)

MBzP

1.27

(0.79, 1.65)

1.15

(1.03, 1.27)

−0.60%

(−1.63, 0.43%)

MBP

1.35

(0.99, 1.87)

1.17

(1.05, 1.29)

−0.74%

(−1.75, 0.28%)

MiBP

0.98

(0.66, 1.45)

1.00

(0.90, 1.12)

0.30%

(−0.82, 1.44%)

MEP

1.22

(0.87, 1.71)

1.01

(0.91, 1.12)

−0.11%

(−1.06, 0.86%)

MCPP

1.27

(0.93, 1.72)

1.10

(1.01, 1.20)

−0.28%

(−1.18, 0.62%)

  1. Phthalates were averaged across the first three visits and log-transformed. All models were adjusted for average specific gravity, maternal age at first visit, race, and education. The single-pollutant models for MBzP, MBP, MiBP, MEP, and MCPP are also adjusted for health insurance provider. Bolded cells indicate significant (p < 0.05) odds ratios (OR), hazard ratios (HR), and percent changes (% Change). Odds ratios, hazard ratios and percent changes are all calculated on IQR (Interquartile Range) scale. Abbreviations: CI, Confidence Interval; Logistic, Logistic Regression; Cox, Cox Proportional Hazards Model; AFT, Accelerated Failure Time Model; MEHP, Mono-(2-ethyl)-hexyl phthalate; MEHHP, Mono-(2-ethyl-5-hydroxyhexyl) phthalate; MEOHP, Mono-(2-ethyl-5-oxohexyl) phthalate; MECPP, Mono-(2-ethyl-5-carboxypentyl) phthalate; Σ DEHP, Summed DEHP metabolites; MBzP, Mono-benzyl phthalate; MBP, Mono-n-butyl phthalate; MiBP, Mono-isobutyl phthalate; MEP, Mono-ethyl phthalate; MCPP, Mono-(3-carboxypropyl) phthalate. *Results are similar to Ferguson and colleagues (2014) [14]