Phthalate Metabolite | Logistic | Cox | AFT |
|---|
OR | 95% CI | HR | 95% CI | % Change | 95% CI |
|---|
MEHP |
1.40
|
(1.06, 1.85)
| 1.03 | (0.96, 1.12) | −0.52% | (−1.28, 0.26%) |
MEHHP | 0.97 | (0.74, 1.26) | 0.98 | (0.91, 1.07) | −0.14% | (−0.90, 0.63%) |
MEOHP | 1.10 | (0.85, 1.42) | 1.02 | (0.95, 1.10) | −0.33% | (−1.07, 0.40%) |
MECPP |
1.43
|
(1.12, 1.83)
|
1.11
|
(1.03, 1.19)
|
−0.74%
|
(−1.14, − 0.03%)
|
Σ DEHP |
1.32
|
(1.01, 1.74)
| 1.07 | (0.99, 1.16) | −0.64% | (−1.14, 0.13%) |
MBzP | 1.08 | (0.81, 1.42) |
1.13
|
(1.05, 1.22)
| −0.50% | (−1.28, 0.28%) |
MBP | 1.18 | (0.97, 1.46) |
1.11
|
(1.04, 1.19)
| −0.44% | (−1.11, 0.24%) |
MiBP | 0.93 | (0.72, 1.19) | 0.98 | (0.92, 1.05) | 0.33% | (−0.38, 1.04%) |
MEP | 1.10 | (0.82, 1.46) | 0.98 | (0.90, 1.06) | 0.04% | (−0.78, 0.87%) |
MCPP | 1.19 | (0.95, 1.48) |
1.06
|
(1.00, 1.12)
| −0.19% | (−0.84, 0.46%) |
- Phthalate measurements at each visit were log-transformed. All models were adjusted for specific gravity at the respective visit, time of sample collection, maternal age at first visit, race, and education. The single-pollutant models for MBzP, MBP, MiBP, MEP, and MCPP are also adjusted for health insurance provider. Bolded cells indicate significant (p < 0.05) odds ratios (OR), hazard ratios (HR), and percent changes (% Change). Odds ratios, hazard ratios and percent changes are all calculated on IQR (Interquartile Range) scale. Abbreviations: CI, Confidence Interval; Logistic, Logistic Regression; Cox, Cox Proportional Hazards Model; AFT, Accelerated Failure Time Model; MEHP, Mono-(2-ethyl)-hexyl phthalate; MEHHP, Mono-(2-ethyl-5-hydroxyhexyl) phthalate; MEOHP, Mono-(2-ethyl-5-oxohexyl) phthalate; MECPP, Mono-(2-ethyl-5-carboxypentyl) phthalate; Σ DEHP, Summed DEHP metabolites; MBzP, Mono-benzyl phthalate; MBP, Mono-n-butyl phthalate; MiBP, Mono-isobutyl phthalate; MEP, Mono-ethyl phthalate; MCPP, Mono-(3-carboxypropyl) phthalate
