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Table 2 Significant superpathways and subpathways in pathway enrichment analysis

From: Welding fume exposure is associated with inflammation: a global metabolomics profiling study

Pathway Number Different Percentage (%) Upa Downa P FDR-q
Superpathway
 Lipid 321 61 19 37 24 2.18E-56 1.75E-55
 Amino acid 158 22 13.92 19 3 7.37E-19 2.95E-18
 Xenobiotics 97 10 8.77 10 0 9.41E-09 2.51E-08
 Carbohydrate 21 8 38.09 7 1 4.04E-07 8.08E-07
 Cofactors and vitamins 20 5 25 0 5 1.07E-04 1.71E-04
 Nucleotide 30 4 13.33 2 2 6.76E-04 9.01E-04
 Energy 9 2 22.22 2 0 2.64E-02 3.02E-02
Subpathway
 Lysolipid 24 10 41.67 10 0 1.91E-07 7.84E-06
 Phospholipid Metabolism 33 8 24.24 8 0 4.47E-06 9.17E-05
 Fatty Acid Metabolism (Acyl Carnitine) 23 7 30.43 0 7 2.14E-05 1.75E-04
 Food Component/Plant 31 7 22.58 7 0 2.14E-05 1.75E-04
 Phenylalanine and Tyrosine Metabolism 29 7 24.14 6 1 2.14E-05 1.75E-04
 Polyunsaturated Fatty Acid (n3 and n6) 13 6 46.15 1 5 1.02E-04 6.94E-04
 Diacylglycerol 19 5 26.32 5 0 4.79E-04 2.80E-03
 Fatty Acid, Monohydroxy 14 4 28.57 2 2 2.24E-03 8.35E-03
 Hemoglobin and Porphyrin Metabolism 5 4 80.00 0 4 2.24E-03 8.35E-03
 Leucine, Isoleucine and Valine Metabolism 24 4 16.67 3 1 2.24E-03 8.35E-03
 Steroid 36 4 11.11 0 4 2.24E-03 8.35E-03
 Endocannabinoid 5 3 60.00 0 3 1.04E-02 3.05E-02
 Fructose, Mannose and Galactose Metabolism 4 3 75.00 2 1 1.04E-02 3.05E-02
 Pentose Metabolism 6 3 50.00 3 0 1.04E-02 3.05E-02
  1. aUp indicates higher level in the post-exposure group; down indicates lower level in the post-exposure group