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Table 4 Effects of glyphosate or Roundup Bioflow exposure on sperm parameters

From: The Ramazzini Institute 13-week pilot study glyphosate-based herbicides administered at human-equivalent dose to Sprague Dawley rats: effects on development and endocrine system

Parameter 6-week cohort 13-week cohort
Control Glyphosate Roundup Control Glyphosate Roundup
No. of males examined 8 8 8 10 10 10
Sperm number (× 106/g testis)a 90.3 ± 22.0 83.7 ± 15.6 81.0 ± 12.0 109.4 ± 17.9 107.9 ± 11.3 119.6 ± 20.2
Daily sperm production (× 106/g testis)a 14.8 ± 3.6 13.7 ± 2.6 13.3 ± 2.0 17.9 ± 2.9 17.7 ± 1.8 19.6 ± 3.3
Cauda epididimal sperm number (× 106)a 51.2 ± 10.5 51.9 ± 10.5 50.9 ± 10.7 129.5 ± 28.5 125.9 ± 14.0 122.7 ± 11.0
Caput/corpus epididimal sperm number (× 106)a 67.6 ± 6.1 66.5 ± 7.9 66.5 ± 10.6 97.0 ± 16.4 93.3 ± 13.0 93.2 ± 8.8
Sperm transit time through caput + corpus of epididymis (days)a 4.8 ± 1.3 5.0 ± 1.1 5.1 ± 1.0 5.5 ± 0.8 5.3 ± 1.0 4.8 ± 0.7
Sperm transit time through cauda of epididymis (days)a 3.5 ± 0.5 3.8 ± 0.8 3.9 ± 0.8 7.4 ± 1.8 7.2 ± 0.9 6.4 ± 1.1
Sperm transit time through epididymis in toto (days)a 8.3 ± 1.7 8.8 ± 1.5 8.9 ± 1.8 12.8 ± 2.2 12.5 ± 1.7 11.2 ± 1.7
Total abnormal sperm (%)a 6.3 ± 1.3 6.4 ± 1.8 6.3 ± 1.4 4.6 ± 1.4 4.3 ± 1.9 3.5 ± 1.3
  1. a:Mean ± standard deviation