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Table 4 Effects of glyphosate or Roundup Bioflow exposure on sperm parameters

From: The Ramazzini Institute 13-week pilot study glyphosate-based herbicides administered at human-equivalent dose to Sprague Dawley rats: effects on development and endocrine system

Parameter

6-week cohort

13-week cohort

Control

Glyphosate

Roundup

Control

Glyphosate

Roundup

No. of males examined

8

8

8

10

10

10

Sperm number (× 106/g testis)a

90.3 ± 22.0

83.7 ± 15.6

81.0 ± 12.0

109.4 ± 17.9

107.9 ± 11.3

119.6 ± 20.2

Daily sperm production (× 106/g testis)a

14.8 ± 3.6

13.7 ± 2.6

13.3 ± 2.0

17.9 ± 2.9

17.7 ± 1.8

19.6 ± 3.3

Cauda epididimal sperm number (× 106)a

51.2 ± 10.5

51.9 ± 10.5

50.9 ± 10.7

129.5 ± 28.5

125.9 ± 14.0

122.7 ± 11.0

Caput/corpus epididimal sperm number (× 106)a

67.6 ± 6.1

66.5 ± 7.9

66.5 ± 10.6

97.0 ± 16.4

93.3 ± 13.0

93.2 ± 8.8

Sperm transit time through caput + corpus of epididymis (days)a

4.8 ± 1.3

5.0 ± 1.1

5.1 ± 1.0

5.5 ± 0.8

5.3 ± 1.0

4.8 ± 0.7

Sperm transit time through cauda of epididymis (days)a

3.5 ± 0.5

3.8 ± 0.8

3.9 ± 0.8

7.4 ± 1.8

7.2 ± 0.9

6.4 ± 1.1

Sperm transit time through epididymis in toto (days)a

8.3 ± 1.7

8.8 ± 1.5

8.9 ± 1.8

12.8 ± 2.2

12.5 ± 1.7

11.2 ± 1.7

Total abnormal sperm (%)a

6.3 ± 1.3

6.4 ± 1.8

6.3 ± 1.4

4.6 ± 1.4

4.3 ± 1.9

3.5 ± 1.3

  1. a:Mean ± standard deviation