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Table 6 Organ weights of male offspring

From: The Ramazzini Institute 13-week pilot study glyphosate-based herbicides administered at human-equivalent dose to Sprague Dawley rats: effects on development and endocrine system

 

6-week cohort

13-week cohort

Control

Glyphosate

Roundup

Control

Glyphosate

Roundup

No. of males examined

8

8

8

10

10

10

Body weight (g)a

321 ± 19

326 ± 16

317 ± 23

458 ± 19

454 ± 19

449 ± 15

Adrenal glandsa, b

0.070 ± 0.014

[0.022 ± 0.005]

0.071 ± 0.015

[0.022 ± 0.004]

0.063 ± 0.009

[0.020 ± 0.002]

0.085 ± 0.025

[0.019 ± 0.005]

0.083 ± 0.024

[0.018 ± 0.005]

0.144 ± 0.190

[0.032 ± 0.041]

Testisa, b

1.475 ± 0.052

[0.461 ± 0.023]

1.474 ± 0.077

[0.453 ± 0.023]

1.459 ± 0.100

[0.460 ± 0.017]

1.568 ± 0.065

[0.342 ± 0.013]

1.529 ± 0.076

[0.337 ± 0.013]

1.562 ± 0.068

[0.347 ± 0.012]

Epididymisa, b

0.370 ± 0.041

[0.115 ± 0.011]

0.343 ± 0.040

[0.105 ± 0.010]

0.368 ± 0.038

[0.116 ± 0.006]

0.595 ± 0.039

[0.130 ± 0.008]

0.563 ± 0.043

[0.124 ± 0.008]

0.553 ± 0.026*

[0.123 ± 0.006]

Bladder/Prostatea, b

0.563 ± 0.080

[0.176 ± 0.026]

0.561 ± 0.099

[0.173 ± 0.036]

0.506 ± 0.090

[0.159 ± 0.022]

0.967 ± 0.086

[0.211 ± 0.024]

0.897 ± 0.160

[0.197 ± 0.033]

0.906 ± 0.190

[0.202 ± 0.045]

Seminal vesicles and coagulating glanda, b

1.129 ± 0.129

[0.353 ± 0.045]

1.110 ± 0.291

[0.339 ± 0.083]

1.235 ± 0.135

[0.389 ± 0.029]

2.049 ± 0.418

[0.446 ± 0.083]

1.879 ± 0.298

[0.414 ± 0.063]

2.055 ± 0.404

[0.457 ± 0.090]

  1. *Statistically significant with Dunnett’s test (p < 0.05)
  2. aMean ± standard deviation
  3. b:Absolute organ weight (g). In square brackets relative organ weight (organ weight / body weight ratio *100)