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Table 6 Organ weights of male offspring

From: The Ramazzini Institute 13-week pilot study glyphosate-based herbicides administered at human-equivalent dose to Sprague Dawley rats: effects on development and endocrine system

  6-week cohort 13-week cohort
Control Glyphosate Roundup Control Glyphosate Roundup
No. of males examined 8 8 8 10 10 10
Body weight (g)a 321 ± 19 326 ± 16 317 ± 23 458 ± 19 454 ± 19 449 ± 15
Adrenal glandsa, b 0.070 ± 0.014
[0.022 ± 0.005]
0.071 ± 0.015
[0.022 ± 0.004]
0.063 ± 0.009
[0.020 ± 0.002]
0.085 ± 0.025
[0.019 ± 0.005]
0.083 ± 0.024
[0.018 ± 0.005]
0.144 ± 0.190
[0.032 ± 0.041]
Testisa, b 1.475 ± 0.052
[0.461 ± 0.023]
1.474 ± 0.077
[0.453 ± 0.023]
1.459 ± 0.100
[0.460 ± 0.017]
1.568 ± 0.065
[0.342 ± 0.013]
1.529 ± 0.076
[0.337 ± 0.013]
1.562 ± 0.068
[0.347 ± 0.012]
Epididymisa, b 0.370 ± 0.041
[0.115 ± 0.011]
0.343 ± 0.040
[0.105 ± 0.010]
0.368 ± 0.038
[0.116 ± 0.006]
0.595 ± 0.039
[0.130 ± 0.008]
0.563 ± 0.043
[0.124 ± 0.008]
0.553 ± 0.026*
[0.123 ± 0.006]
Bladder/Prostatea, b 0.563 ± 0.080
[0.176 ± 0.026]
0.561 ± 0.099
[0.173 ± 0.036]
0.506 ± 0.090
[0.159 ± 0.022]
0.967 ± 0.086
[0.211 ± 0.024]
0.897 ± 0.160
[0.197 ± 0.033]
0.906 ± 0.190
[0.202 ± 0.045]
Seminal vesicles and coagulating glanda, b 1.129 ± 0.129
[0.353 ± 0.045]
1.110 ± 0.291
[0.339 ± 0.083]
1.235 ± 0.135
[0.389 ± 0.029]
2.049 ± 0.418
[0.446 ± 0.083]
1.879 ± 0.298
[0.414 ± 0.063]
2.055 ± 0.404
[0.457 ± 0.090]
  1. *Statistically significant with Dunnett’s test (p < 0.05)
  2. aMean ± standard deviation
  3. b:Absolute organ weight (g). In square brackets relative organ weight (organ weight / body weight ratio *100)